Varaico: Literature-Extracted Genetic Variants

Gene:TLR9
Variant:p.Y870F
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TLR9

NM_017442.4:p.Y870F

Associated Papers

TLR9 signaling requires ligand-induced phosphorylation of two specific tyrosine residues by EGFR and Syk.

Veleeparambil M et al.

Mbio, 2025

Tyrosine 870 of TLR9 is critical for receptor maturation rather than phosphorylation-dependent ligand-induced signaling.

Biswas C et al.

Plos One, 2018

TLR9 stability and signaling are regulated by phosphorylation and cell stress.

Hasan M et al.

Journal of Leukocyte Biology, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."