Varaico: Literature-Extracted Genetic Variants

Gene:TLR9
Variant:p.R702W
Back to variants list

TLR9

NM_017442.4:p.R702W

Associated Papers

Common inherited loss-of-function mutations in the innate sensor NOD2 contribute to exceptional immune response to cancer immunotherapy.

Barnet MB et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025

Goblet Cell Loss Linked to NOD2 and Secondary Resection in Crohn's Disease Is Induced by Dysbiosis and Epithelial MyD88.

Wong SY et al.

Cellular and Molecular Gastroenterology and Hepatology, 2025

NOD2-mediated dual negative regulation of inflammatory responses triggered by TLRs in the gastrointestinal tract.

Masaki S et al.

Frontiers in Immunology, 2024

Germline variants in UNC13D and AP3B1 are enriched in COVID-19 patients experiencing severe cytokine storms.

Luo H et al.

European Journal of Human Genetics : Ejhg, 2021

33867526 (PubMed )
Supplement: 41431_2021_886_MOESM2_ESM.xlsx › TableS4

Host genetic variants in sepsis risk: a field synopsis and meta-analysis.

Lu H et al.

Critical Care (london, England), 2019

30683156 (PubMed )
Supplement: 13054_2019_2313_MOESM1_ESM.docx

Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.

Gresnigt MS et al.

Nature Communications, 2018

Genetic variation of the Toll-like receptors in a Swedish allergic rhinitis case population.

Henmyr V et al.

Bmc Medical Genetics, 2017

28228119 (PubMed )
Supplement: 12881_2017_379_MOESM8_ESM.xlsx › TabS4

Epistatic interaction between TLR4 and NOD2 in patients with Crohn's Disease: relation with risk and phenotype in a Spanish cohort.

Martinez-Chamorro A et al.

Immunobiology, 2016

Role of Nucleotide-binding and Oligomerization Domain 2 Protein (NOD2) in the Development of Atherosclerosis.

Kim HJ

The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2015

NOD2/CARD15 single nucleotide polymorphism 13 (3020insC) is associated with risk of sepsis and single nucleotide polymorphism 8 (2104C>T) with herpes viruses reactivation in patients after allogeneic hematopoietic stem cell transplantation.

Jaskula E et al.

Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation, 2014

A two-marker haplotype in the IRF5 gene is associated with inflammatory bowel disease in a North American cohort.

Gathungu G et al.

Genes and Immunity, 2012

Toll-like receptor 9, NOD2 and IL23R gene polymorphisms influenced outcome in AML patients transplanted from HLA-identical sibling donors.

Elmaagacli AH et al.

Bone Marrow Transplantation, 2011

The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.

Glas J et al.

Plos One, 2010

Toll-like receptor 9 gene mutations and polymorphisms in Japanese ulcerative colitis patients.

Fuse K et al.

World Journal of Gastroenterology, 2010

Pyrosequencing of toll-like receptor polymorphisms of functional relevance.

Ahmad-Nejad P

Methods in Molecular Biology (clifton, N.j.), 2009

Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene.

Cummings JR et al.

Inflammatory Bowel Diseases, 2007

CARD15/NOD2 mutations in Crohn's disease.

Hugot JP

Annals of the New York Academy of Sciences, 2006

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."