Associated Papers
Lysosomal TMEM165 controls cellular ion homeostasis and survival by mediating lysosomal Ca2+ import and H+ efflux.
Chen R et al.
Nature Communications, 2025
Insights into molecular and cellular functions of the Golgi calcium/manganese-proton antiporter TMEM165.
Jankauskas SS et al.
The Journal of Biological Chemistry, 2024
Splice-Modulating Antisense Oligonucleotides as Therapeutics for Inherited Metabolic Diseases.
Chen S et al.
Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy, 2024
TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy.
Khan S et al.
Cell Death & Disease, 2021
Skeletal and Bone Mineral Density Features, Genetic Profile in Congenital Disorders of Glycosylation: Review.
Lipiński P et al.
Diagnostics (basel, Switzerland), 2021
Biometals and glycosylation in humans: Congenital disorders of glycosylation shed lights into the crucial role of Golgi manganese homeostasis.
Foulquier F et al.
Biochimica Et Biophysica Acta. General Subjects, 2020
Sugary Logistics Gone Wrong: Membrane Trafficking and Congenital Disorders of Glycosylation.
Linders PTA et al.
International Journal of Molecular Sciences, 2020
The human Golgi protein TMEM165 transports calcium and manganese in yeast and bacterial cells.
Stribny J et al.
The Journal of Biological Chemistry, 2020
Integrating glycomics and genomics uncovers SLC10A7 as essential factor for bone mineralization by regulating post-Golgi protein transport and glycosylation.
Ashikov A et al.
Human Molecular Genetics, 2018
TMEM165 deficiencies in Congenital Disorders of Glycosylation type II (CDG-II): Clues and evidences for roles of the protein in Golgi functions and ion homeostasis.
Dulary E et al.
Tissue & Cell, 2017
Evidence for splice transcript variants of TMEM165, a gene involved in CDG.
Krzewinski-Recchi MA et al.
Biochimica Et Biophysica Acta. General Subjects, 2017
Abnormal cartilage development and altered N-glycosylation in Tmem165-deficient zebrafish mirrors the phenotypes associated with TMEM165-CDG.
Bammens R et al.
Glycobiology, 2015
Antisense-mediated therapeutic pseudoexon skipping in TMEM165-CDG.
Yuste-Checa P et al.
Clinical Genetics, 2015
Impact of disease-causing mutations on TMEM165 subcellular localization, a recently identified protein involved in CDG-II.
Rosnoblet C et al.
Human Molecular Genetics, 2013
Newly characterized Golgi-localized family of proteins is involved in calcium and pH homeostasis in yeast and human cells.
Demaegd D et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013
TMEM165 deficiency causes a congenital disorder of glycosylation.
Foulquier F et al.
American Journal of Human Genetics, 2012