Varaico: Literature-Extracted Genetic Variants

Gene:TMPRSS2
Variant:p.V160M
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TMPRSS2

NM_005656.4:p.V160M

Associated Papers

TMPRSS2 rs12329760 variant as a prognostic marker for prostate cancer progression.

Elghazali K et al.

Molecular Biology Reports, 2026

Exploring the genetic landscape of COVID-19 susceptibility and severity among patients in Türkiye.

Er AG et al.

Bmc Medical Genomics, 2025

Deep Sequencing Reveals Novel Mutations in Androgen Receptor-Related Genes in Prostate Cancer.

Pedroza-Torres A et al.

International Journal of Molecular Sciences, 2025

41009328 (PubMed )
Supplement: ijms-26-08758-s001.zip › Suppl_Table_1.xlsx › Hoja1

Antiviral Intervention of COVID-19: Linkage of Disease Severity with Genetic Markers FGB (rs1800790), NOS3 (rs2070744) and TMPRSS2 (rs12329760).

Sokolenko M et al.

Viruses, 2025

Association of VDR and TMPRSS2 gene polymorphisms with COVID-19 severity: a computational and clinical study.

Verma S et al.

Molecular Biology Reports, 2025

Genetics of Long COVID: Exploring the Molecular Drivers of Persistent Pulmonary Vascular Disease Symptoms.

Ayyoub S et al.

Infectious Disease Reports, 2025

Role of ACE2 and TMPRSS2 polymorphisms on COVID-19 outcome and disease severity in adult patients: A prospective cohort study in a tertiary hospital, Indonesia.

Yunita R et al.

Narra J, 2024

Patient tissue-derived FGFR4-variant and wild-type colorectal cancer organoid development and anticancer drug sensitivity testing.

Lin H et al.

Heliyon, 2024

38826758 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_1

Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.

Vanni I et al.

Journal of Translational Medicine, 2024

38750555 (PubMed )
Supplement: 12967_2024_5227_MOESM14_ESM.xlsx › S14

Genetic variant in complement receptor 1 (CR1, CD35) is associated with a cluster of severe fatal COVID-19 in a family.

Danial-Farran N et al.

The Journal of Infection, 2023

36924837 (PubMed )
Supplement: mmc2.xlsx › ______1

ACE2 and TMPRSS2 SARS-CoV-2 infectivity genes: deep mutational scanning and characterization of missense variants.

Zhang L et al.

Human Molecular Genetics, 2022

Analysis of ACE2 and TMPRSS2 coding variants as a risk factor for SARS-CoV-2 from 946 whole-exome sequencing data in the Turkish population.

Duman N et al.

Journal of Medical Virology, 2022

Gene variants in pro-coagulant and anti-coagulant genes could be prognostic genetic markers of COVID-19 susceptibility.

Srivastava S et al.

Heliyon, 2022

The association of COVID-19 severity and susceptibility and genetic risk factors: A systematic review of the literature.

Ishak A et al.

Gene, 2022

Association of TMPRSS2 Gene Polymorphisms with COVID-19 Severity and Mortality: a Case-Control Study with Computational Analyses.

Rokni M et al.

Applied Biochemistry and Biotechnology, 2022

Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection.

Zhang C et al.

Proceedings of the National Academy of Sciences of the United States of America, 2022

A common TMPRSS2 variant has a protective effect against severe COVID-19.

David A et al.

Current Research in Translational Medicine, 2022

Investigating underlying human immunity genes, implicated diseases and their relationship to COVID-19.

Ahmed Z et al.

Personalized Medicine, 2022

Polymorphisms and mutations of ACE2 and TMPRSS2 genes are associated with COVID-19: a systematic review.

Li J et al.

European Journal of Medical Research, 2022

In Silico Molecular Characterization of Human TMPRSS2 Protease Polymorphic Variants and Associated SARS-CoV-2 Susceptibility.

Salleh MZ et al.

Life (basel, Switzerland), 2022

An overview of human proteins and genes involved in SARS-CoV-2 infection.

Jahanafrooz Z et al.

Gene, 2022

Human genetic basis of severe or critical illness in COVID-19.

Ji XS et al.

Frontiers in Cellular and Infection Microbiology, 2022

rs12329760 Polymorphism in Transmembrane Serine Protease 2 Gene and Risk of Coronavirus Disease 2019 Mortality.

Beheshti Shirazi SS et al.

Biomed Research International, 2022

TMPRSS2 gene polymorphism common in East Asians confers decreased COVID-19 susceptibility.

Sekiya T et al.

Frontiers in Microbiology, 2022

Host genetics of pediatric SARS-CoV-2 COVID-19 and multisystem inflammatory syndrome in children.

Schulert GS et al.

Current Opinion in Pediatrics, 2021

A variant in TMPRSS2 is associated with decreased disease severity in COVID-19.

Ravikanth V et al.

Meta Gene, 2021

Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection.

Zhang C et al.

Medrxiv : the Preprint Server for Health Sciences, 2021

Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection.

Zhang C et al.

Research Square, 2021

Hypotheses and facts for genetic factors related to severe COVID-19.

Kotsev SV et al.

World Journal of Virology, 2021

Initial study on TMPRSS2 p.Val160Met genetic variant in COVID-19 patients.

Wulandari L et al.

Human Genomics, 2021

Genes, COVID-19 and phenotype.

Izzedine H et al.

Clinical Kidney Journal, 2021

Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer.

Liu S et al.

Communications Biology, 2021

33907296 (PubMed )
Supplement: 42003_2021_2024_MOESM11_ESM.xlsx › Supplementary_Data_8

Protective Role of a TMPRSS2 Variant on Severe COVID-19 Outcome in Young Males and Elderly Women.

Monticelli M et al.

Genes, 2021

Immunogenetic Predictors of Severe COVID-19.

Malkova A et al.

Vaccines, 2021

Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19.

Choudhary S et al.

Annals of Laboratory Medicine, 2021

A synergetic effect of BARD1 mutations on tumorigenesis.

Li W et al.

Nature Communications, 2021

33623049 (PubMed )
Supplement: 41467_2021_21519_MOESM5_ESM.xlsx › sheet1

Genetic variability in COVID-19-related genes in the Brazilian population.

Secolin R et al.

Human Genome Variation, 2021

Genetics Insight for COVID-19 Susceptibility and Severity: A Review.

Fricke-Galindo I et al.

Frontiers in Immunology, 2021

Transmembrane serine protease 2 Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection: A German Case-Control Study.

Schönfelder K et al.

Frontiers in Genetics, 2021

Computational Analysis of Missense Variants in the Human Transmembrane Protease Serine 2 (TMPRSS2) and SARS-CoV-2.

Saih A et al.

Biomed Research International, 2021

Variability in genes related to SARS-CoV-2 entry into host cells (ACE2, TMPRSS2, TMPRSS11A, ELANE, and CTSL) and its potential use in association studies.

Vargas-Alarcón G et al.

Life Sciences, 2020

New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis.

Hou Y et al.

Bmc Medicine, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."