Varaico: Literature-Extracted Genetic Variants

Gene:TNF
Variant:p.E183A
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TNF

NM_000594.4:p.E183A

Associated Papers

The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.

Verstak B et al.

Journal of Leukocyte Biology, 2014

Mutational analysis identifies residues crucial for homodimerization of myeloid differentiation factor 88 (MyD88) and for its function in immune cells.

Loiarro M et al.

The Journal of Biological Chemistry, 2013

Mutational analysis and molecular modeling of the N-terminal kringle-containing domain of hepatocyte growth factor identifies amino acid side chains important for interaction with the c-Met receptor.

Lokker NA et al.

Protein Engineering, 1994

Region of a conserved sequence motif in a class II tRNA synthetase needed for transfer of an activated amino acid to an RNA substrate.

Shi JP et al.

Biochemistry, 1994

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."