Associated Papers
Rare variant association analysis in 51,256 type 2 diabetes cases and 370,487 controls informs the spectrum of pathogenicity of monogenic diabetes genes.
Schroeder P et al.
Medrxiv : the Preprint Server for Health Sciences, 2023
The impact of the cytoplasmic ubiquitin ligase TNFAIP3 gene variation on transcription factor NF-κB activation in acute kidney injury.
Rogers NM et al.
Kidney International, 2023
TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation.
Zammit NW et al.
Frontiers in Immunology, 2022
Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach.
Akhtar M et al.
Biology, 2021
Genetic Landscape of Rare Autoinflammatory Disease Variants in Qatar and Middle Eastern Populations Through the Integration of Whole-Genome and Exome Datasets.
Sharma P et al.
Frontiers in Genetics, 2021
A20 at the Crossroads of Cell Death, Inflammation, and Autoimmunity.
Martens A et al.
Cold Spring Harbor Perspectives in Biology, 2020
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
Fragoza R et al.
Nature Communications, 2019
Disseminated and Congenital Toxoplasmosis in a Mother and Child With Activated PI3-Kinase δ Syndrome Type 2 (APDS2): Case Report and a Literature Review of Toxoplasma Infections in Primary Immunodeficiencies.
Karanovic D et al.
Frontiers in Immunology, 2019
A20/Tumor Necrosis Factor α-Induced Protein 3 in Immune Cells Controls Development of Autoinflammation and Autoimmunity: Lessons from Mouse Models.
Das T et al.
Frontiers in Immunology, 2018
Single nucleotide polymorphisms in TNFAIP3 were associated with the risks of rheumatoid arthritis in northern Chinese Han population.
Zhang X et al.
Bmc Medical Genetics, 2014
Single nucleotide polymorphisms at the TNFAIP3/A20 locus and susceptibility/resistance to inflammatory and autoimmune diseases.
Mele A et al.
Advances in Experimental Medicine and Biology, 2014
TNFAIP3 rs2230926 polymorphisms in rheumatoid arthritis of southern Chinese Han population: a case-control study.
Hao G et al.
International Journal of Clinical and Experimental Pathology, 2014
A20: linking a complex regulator of ubiquitylation to immunity and human disease.
Ma A et al.
Nature Reviews. Immunology, 2012
Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease.
Vereecke L et al.
Biochemical Society Transactions, 2011
Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
Adrianto I et al.
Nature Genetics, 2011
African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity.
Lodolce JP et al.
Journal of Immunology (baltimore, Md. : 1950), 2010