Associated Papers
Germline Variants in the Immune Response-Related Genes: Possible Modifying Effect on Age-Dependent BRCA1 Penetrance in Breast Cancer Patient.
Kuligina ES et al.
Cancers, 2025
Molecular Determinants of the Human Retinal Pigment Epithelium Cell Fate and Potential Pharmacogenomic Targets for Precision Medicine.
Zibetti C
International Journal of Molecular Sciences, 2025
The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.
Wang LY et al.
Innovation (cambridge (mass.)), 2025
Pharmacogenomic landscape of TNF inhibitors in the Middle Eastern Qatari population.
Jan Z et al.
Frontiers in Immunology, 2025
Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.
Vanni I et al.
Journal of Translational Medicine, 2024
The Complexity of Being A20: From Biological Functions to Genetic Associations.
Karri U et al.
Journal of Clinical Immunology, 2024
Interactions between TNFAIP3, PTPN22, and TRAF1-C5 gene polymorphisms in patients with primary Sjögren's syndrome.
Cadena-Sandoval D et al.
Archives of Rheumatology, 2024
The functional TNFAIP3 rs2230926T/G (Phe127Cys) variant confers risk to systemic lupus erythematosus in a Latin American population.
Montúfar-Robles I et al.
Human Immunology, 2024
A20 Promoter rs5029924 Concomitant with rs2230926 and rs5029937 May Be a Prognostic Predictor for Joint Deformity or Refractory Rheumatoid Arthritis.
Zhu L et al.
International Journal of General Medicine, 2024
Case report: Adult case of A20 haploinsufficiency suspected as neuro-Behçet disease.
Shirai H et al.
Frontiers in Immunology, 2024
A critical region of A20 unveiled by missense TNFAIP3 variations that lead to autoinflammation.
El Khouri E et al.
Elife, 2023
The impact of the cytoplasmic ubiquitin ligase TNFAIP3 gene variation on transcription factor NF-κB activation in acute kidney injury.
Rogers NM et al.
Kidney International, 2023
Molecular Dynamic Simulations Unravel the Underlying Impact of Missense Mutation in Autoimmunity Gene PTPN22 on Predisposition to Rheumatoid Arthritis.
Pasha U et al.
Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research, 2023
Application of circulating tumour DNA in terms of prognosis prediction in Chinese follicular lymphoma patients.
Zhao M et al.
Frontiers in Genetics, 2023
No association of eight TNFAIP3 single nucleotide variants to rheumatoid arthritis in Mexicans.
Aranda-Uribe IS et al.
Molecular Biology Reports, 2022
Clinicopathologic Characteristics and A20 Mutation in Primary Thyroid Lymphoma.
Kuribayashi-Hamada Y et al.
Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi, 2022
TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation.
Zammit NW et al.
Frontiers in Immunology, 2022
Three Chinese pedigrees of A20 haploinsufficiency: clinical, cytokine and molecular characterization.
Tian Y et al.
Frontiers in Immunology, 2022
TNFAIP3 mutation may be associated with favorable overall survival for patients with T-cell lymphoma.
Chen C et al.
Cancer Cell International, 2021
Functional analysis of novel A20 variants in patients with atypical inflammatory diseases.
Kadowaki S et al.
Arthritis Research & Therapy, 2021
Genetic Landscape of Rare Autoinflammatory Disease Variants in Qatar and Middle Eastern Populations Through the Integration of Whole-Genome and Exome Datasets.
Sharma P et al.
Frontiers in Genetics, 2021
A20 Haploinsufficiency in East Asia.
Kadowaki T et al.
Frontiers in Immunology, 2021
The haplotypes of various TNF related genes associated with scleritis in Chinese Han.
Gao Y et al.
Human Genomics, 2020
Paediatric-onset haploinsufficiency of A20 associated with a novel and de novo nonsense TNFAIP3 mutation.
Endo Y et al.
Rheumatology (oxford, England), 2020
Variants of genes encoding TNF receptors and ligands and proteins regulating TNF activation in familial multiple sclerosis.
Torre-Fuentes L et al.
Cns Neuroscience & Therapeutics, 2020
Genomics of lethal prostate cancer at diagnosis and castration resistance.
Mateo J et al.
The Journal of Clinical Investigation, 2020
A20 at the Crossroads of Cell Death, Inflammation, and Autoimmunity.
Martens A et al.
Cold Spring Harbor Perspectives in Biology, 2020
Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus.
Odqvist L et al.
Annals of the Rheumatic Diseases, 2019
Analysis of circulating tumor DNA by targeted ultra-deep sequencing across various non-Hodgkin lymphoma subtypes.
Shin SH et al.
Leukemia & Lymphoma, 2019
Role of deleterious single nucleotide variants in the coding regions of TNFAIP3 for Japanese autoimmune hepatitis with cirrhosis.
Higuchi T et al.
Scientific Reports, 2019
Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug resistance.
Vikova V et al.
Theranostics, 2019
Identification of functional missense single-nucleotide polymorphisms in TNFAIP3 in a predominantly Hispanic population.
Zhang B et al.
Journal of Clinical and Translational Science, 2018
Different genetic alteration of A20 in a Sézary syndrome case with Vα2-Jα22 T cell clone.
Zhou L et al.
Asia-pacific Journal of Clinical Oncology, 2018
An Autoimmune Disease-Associated Risk Variant in the TNFAIP3 Gene Plays a Protective Role in Brucellosis That Is Mediated by the NF-κB Signaling Pathway.
Lou L et al.
Journal of Clinical Microbiology, 2018
Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.
Schrader A et al.
Nature Communications, 2018
A20/Tumor Necrosis Factor α-Induced Protein 3 in Immune Cells Controls Development of Autoinflammation and Autoimmunity: Lessons from Mouse Models.
Das T et al.
Frontiers in Immunology, 2018
TNFAIP3 F127C Coding Variation in Greek Primary Sjogren's Syndrome Patients.
Nezos A et al.
Journal of Immunology Research, 2018
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
Ferreira MA et al.
Nature Genetics, 2017
Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.
Dand N et al.
Human Molecular Genetics, 2017
Genetic and Functional Associations with Decreased Anti-inflammatory Tumor Necrosis Factor Alpha Induced Protein 3 in Macrophages from Subjects with Axial Spondyloarthritis.
Liu Y et al.
Frontiers in Immunology, 2017
Rheumatoid Arthritis: The Stride from Research to Clinical Practice.
Chung IM et al.
International Journal of Molecular Sciences, 2016
Development of a high-resolution melting method for the screening of TNFAIP3 gene mutations.
Chang YC et al.
Oncology Reports, 2016
Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia.
Johansson P et al.
International Journal of Cancer, 2016