Varaico: Literature-Extracted Genetic Variants

Gene:TNFAIP3
Variant:p.V209V
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TNFAIP3

NM_001270508.2:p.V209V

Associated Papers

A20 controls RANK-dependent osteoclast formation and bone physiology.

Martens A et al.

Embo Reports, 2022

The ubiquitin-editing enzyme A20 regulates synapse remodeling and efficacy.

Mei S et al.

Brain Research, 2020

A20 regulates canonical wnt-signaling through an interaction with RIPK4.

Nakamura BN et al.

Plos One, 2018

Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation.

Wertz IE et al.

Nature, 2015

A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7.

Verhelst K et al.

The Embo Journal, 2012

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation.

Tokunaga F et al.

The Embo Journal, 2012

A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma.

Bellail AC et al.

Cancer Discovery, 2012

African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity.

Lodolce JP et al.

Journal of Immunology (baltimore, Md. : 1950), 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."