Varaico: Literature-Extracted Genetic Variants

Gene:TNFRSF1A
Variant:p.S86T
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TNFRSF1A

NM_001065.4:p.S86T

Associated Papers

Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists.

Mukai Y et al.

Journal of Biochemistry, 2009

Interaction of human TNF and beta2-microglobulin with Tanapox virus-encoded TNF inhibitor, TPV-2L.

Rahman MM et al.

Virology, 2009

Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist.

Shibata H et al.

The Journal of Biological Chemistry, 2008

High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity.

Cha SS et al.

The Journal of Biological Chemistry, 1998

Dissociation of TNF-alpha cytotoxic and proinflammatory activities by p55 receptor- and p75 receptor-selective TNF-alpha mutants.

Barbara JA et al.

The Embo Journal, 1994

Human tumor necrosis factor alpha (TNF alpha) mutants with exclusive specificity for the 55-kDa or 75-kDa TNF receptors.

Loetscher H et al.

The Journal of Biological Chemistry, 1993

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."