Varaico: Literature-Extracted Genetic Variants

Gene:TNFRSF1A
Variant:p.D80N
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TNFRSF1A

NM_001065.4:p.D80N

Associated Papers

TNF-alpha Promoter Single-Nucleotide Polymorphisms and Inflammatory Bowel Diseases in Romania: Association with Disease Susceptibility and Clinical Features.

Țieranu CG et al.

Journal of Clinical Medicine, 2026

The Role of Cytokine Gene Polymorphisms in Rehabilitation Outcome After Traumatic Brain Injury.

Guerini FR et al.

Cells, 2025

A meta-analysis of the association between inflammatory cytokine polymorphism and neonatal sepsis.

Liang J et al.

Plos One, 2024

38848433 (PubMed )
Supplement: pone.0301859.s001.doc

A glaucoma-associated OPTN polymorphism, M98K sensitizes retinal cells to endoplasmic reticulum stress and tumour necrosis factor α.

Sayyad Z et al.

The Febs Journal, 2023

Molecular Evaluation of the Impact of Polymorphic Variants in Apoptotic (Bcl-2/Bax) and Proinflammatory Cytokine (TNF-α/IL-8) Genes on the Susceptibility and Progression of Myeloproliferative Neoplasms: A Case-Control Biomarker Study.

Moawadh MS et al.

Current Issues in Molecular Biology, 2023

Polymorphisms in Lymphotoxin-Alpha as the "Missing Link" in Prognosticating Favourable Response to Omega-3 Supplementation for Dry Eye Disease: A Narrative Review.

Paik B et al.

International Journal of Molecular Sciences, 2023

Association of tumor necrosis factor-alpha promoter region gene polymorphism at positions -308G/A, -857C/T, and -863C/A with etanercept response in Iraqi rheumatoid arthritis patients.

Mohammed S et al.

Archives of Rheumatology, 2022

Association of tumor necrosis factor alpha -308 single nucleotide polymorphism with SARS CoV-2 infection in an Iraqi Kurdish population.

Ali HN et al.

Journal of Clinical Laboratory Analysis, 2022

Tumor Necrosis Factor-alpha (TNF-α) -238 G/A Polymorphism Is Associated with the Treatment Resistance and Attempted Suicide in Schizophrenia.

Aytac HM et al.

Immunological Investigations, 2022

Pharmacogenetics of Biological Agents Used in Inflammatory Bowel Disease: A Systematic Review.

Lauro R et al.

Biomedicines, 2021

The role of single nucleotide polymorphisms of IL-1A -889C>T (rs1800587), TNF-A -238G>A (rs361525), and VDR TaqI (rs731236) on susceptibility to herniated nucleus pulposus: a systematic review and meta-analysis.

Azharuddin A et al.

F1000research, 2021

Association Between TNF-α-308, +489, -238 Polymorphism, and COPD Susceptibility: An Updated Meta-Analysis and Trial Sequential Analysis.

Xia Z et al.

Frontiers in Genetics, 2021

Associations of the -238(G/A) and -308(G/A) TNF-α Promoter Polymorphisms and TNF-α Serum Levels with the Susceptibility to Gastric Precancerous Lesions and Gastric Cancer Related to Helicobacter pylori Infection in a Moroccan Population.

Bounder G et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2020

Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis.

Sode J et al.

Bmc Medical Genetics, 2018

Multiple sclerosis genetics: Results from meta-analyses of candidate-gene association studies.

Tizaoui K

Cytokine, 2018

Genetics in TNF-TNFR pathway: A complex network causing spondyloarthritis and conditioning response to anti-TNFα therapy.

Aita A et al.

Plos One, 2018

Immunology and genetics of tumour necrosis factor in allergic contact dermatitis.

Dittmar D et al.

Contact Dermatitis, 2017

Association between TNF-α-308G>A and -238G>A gene polymorphisms and TNF-α serum levels in Mexican colorectal cancer patients.

Gutiérrez-Hurtado IA et al.

Genetics and Molecular Research : Gmr, 2016

TNF-α gene polymorphisms and expression.

El-Tahan RR et al.

Springerplus, 2016

TNF-alpha gene polymorphisms can help to predict response to etanercept in psoriatic patients.

De Simone C et al.

Journal of the European Academy of Dermatology and Venereology : Jeadv, 2015

TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children.

Rossi E et al.

Plos One, 2015

25915602 (PubMed )
Supplement: pone.0123244.s005.docx

Polymorphisms in the TNF-α, TNFR1 gene and risk of rheumatoid arthritis in Chinese Han population.

Li F et al.

International Journal of Immunogenetics, 2014

Genetic polymorphisms of tumour necrosis factor alpha (TNF-α) promoter gene and response to TNF-α inhibitors in Spanish patients with inflammatory bowel disease.

López-Hernández R et al.

International Journal of Immunogenetics, 2014

HGV&TB: a comprehensive online resource on human genes and genetic variants associated with tuberculosis.

Sahajpal R et al.

Database : the Journal of Biological Databases and Curation, 2014

Roles of tumor necrosis factor alpha gene polymorphisms, tumor necrosis factor alpha level in aqueous humor, and the risks of open angle glaucoma: a meta-analysis.

Xin X et al.

Molecular Vision, 2013

TNF-α -857C>T genotype is predictive of clinical response after treatment with definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma.

Omatsu H et al.

International Journal of Medical Sciences, 2013

Tumor necrosis factor-α gene polymorphisms and risk of oral cancer: evidence from a meta-analysis.

Chen FC et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2013

Effect of the polymorphisms of tumor necrosis factor-α gene on the susceptibility to primary biliary cirrhosis: a meta-analysis.

Qin B et al.

European Journal of Gastroenterology & Hepatology, 2012

Tumor necrosis factor-alpha promoter polymorphisms are associated with idiopathic primary ovarian insufficiency in Korean women.

Kim JH et al.

Fertility and Sterility, 2012

DNA sequence variation and regulation of genes involved in pathogenesis of pulmonary tuberculosis.

Qidwai T et al.

Scandinavian Journal of Immunology, 2012

Pharmacogenetic analysis of TNF, TNFRSF1A, and TNFRSF1B gene polymorphisms and prediction of response to anti-TNF therapy in psoriasis patients in the Greek population.

Vasilopoulos Y et al.

Molecular Diagnosis & Therapy, 2012

TNF-α Polymorphisms in Juvenile Idiopathic Arthritis: Which Potential Clinical Implications?

Scardapane A et al.

International Journal of Rheumatology, 2012

Tumour necrosis factor gene polymorphism and disease prevalence.

Qidwai T et al.

Scandinavian Journal of Immunology, 2011

Association of TLR-4 and TNF-alpha polymorphisms with clinical symptoms and cytokine levels in patients with allergic rhinitis.

Krasznai M et al.

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-rhino-laryngological Societies (eufos) : Affiliated With the German Society for Oto-rhino-laryngology - Head and Neck Surgery, 2011

Tumor necrosis factor-alpha gene polymorphisms are associated with severity of acute graft-versus-host disease following matched unrelated donor bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium study.

Goyal RK et al.

Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation, 2010

TNFA gene promoter polymorphisms and susceptibility to recurrent pregnancy loss in Italian women.

Palmirotta R et al.

Reproductive Sciences (thousand Oaks, Calif.), 2010

Tumour necrosis factor gene polymorphisms and migraine in Greek children.

Pappa S et al.

Archives of Medical Science : Ams, 2010

Does the simultaneous tumor necrosis factor receptor 2, tumor necrosis factor promoter gene polymorphism represent a higher risk for alcoholic liver disease?

Machado MV et al.

European Journal of Gastroenterology & Hepatology, 2009

Association of TNF-alpha and TNFR1 promoters and 3' UTR region of TNFR2 gene polymorphisms with genetic susceptibility to tobacco-related oral carcinoma in Asian Indians.

Gupta R et al.

Oral Oncology, 2008

Associations between tumor necrosis factor-alpha and lymphotoxin-alpha polymorphisms and idiopathic recurrent miscarriage.

Zammiti W et al.

Reproduction (cambridge, England), 2008

A study on the TNF-alpha system in Caucasian Spanish patients with alcoholic liver disease.

Auguet T et al.

Drug and Alcohol Dependence, 2008

Variants in mannose-binding lectin and tumour necrosis factor alpha affect survival in cystic fibrosis.

Buranawuti K et al.

Journal of Medical Genetics, 2007

No evidence for a major effect of tumor necrosis factor alpha gene polymorphisms in periportal fibrosis caused by Schistosoma mansoni infection.

Moukoko CE et al.

Infection and Immunity, 2003

TNF receptor I polymorphism is associated with persistent palindromic rheumatism.

Lu LY et al.

Scandinavian Journal of Rheumatology, 0

The role of tumor necrosis factor (TNF)-alpha and TNF receptor polymorphisms in susceptibility to ankylosing spondylitis.

Chatzikyriakidou A et al.

Clinical and Experimental Rheumatology, 0

Association of tumour necrosis factor-alpha -308 G/A polymorphism with primary open-angle glaucoma.

Bozkurt B et al.

Clinical & Experimental Ophthalmology, 0

Evaluation of Tumor Necrosis Factor Alpha Polymorphism Frequencies in Endometriosis.

Abutorabi R et al.

International Journal of Fertility & Sterility, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."