Varaico: Literature-Extracted Genetic Variants

Gene:TNK2
Variant:p.R99Q
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TNK2

NM_001382273.1:p.R99Q

Associated Papers

Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer.

Kopetz S et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2015

26460303 (PubMed )
Supplement: supp_33.34.4032_DS_2015.632497.pdf

ACK1/TNK2 tyrosine kinase: molecular signaling and evolving role in cancers.

Mahajan K et al.

Oncogene, 2015

Conjunctival melanomas harbor BRAF and NRAS mutations and copy number changes similar to cutaneous and mucosal melanomas.

Griewank KG et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2013

23633454 (PubMed )
Supplement: 10780432ccr130163-sup-tab1-3.pdf

Shepherding AKT and androgen receptor by Ack1 tyrosine kinase.

Mahajan K et al.

Journal of Cellular Physiology, 2010

Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation.

Mahajan K et al.

Plos One, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."