Varaico: Literature-Extracted Genetic Variants

Gene:TNKS2
Variant:p.M1054V
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TNKS2

NM_025235.4:p.M1054V

Associated Papers

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.

Huang SM et al.

Nature, 2009

Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1.

Deng Z et al.

Journal of Virology, 2005

Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner.

Sbodio JI et al.

The Journal of Biological Chemistry, 2002

Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase).

Sbodio JI et al.

The Biochemical Journal, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."