Varaico: Literature-Extracted Genetic Variants

Gene:TNKS2
Variant:p.E1138A
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TNKS2

NM_025235.4:p.E1138A

Associated Papers

Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling.

Mariotti L et al.

Molecular Cell, 2016

27494558 (PubMed )
Supplement: mmc1.pdf

Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs.

Nagy Z et al.

Plos Genetics, 2016

Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.

Guettler S et al.

Cell, 2011

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