Associated Papers
A glycine at position 105 leads to clavulanic acid and avibactam resistance in class A β-lactamases.
Radojković M et al.
The Journal of Biological Chemistry, 2025
Asp179 in the class A β-lactamase from Mycobacterium tuberculosis is a conserved yet not essential residue due to epistasis.
van Alen I et al.
The Febs Journal, 2023
The Effectiveness of Imipenem-Relebactam against Ceftazidime-Avibactam Resistant Variants of the KPC-2 β-Lactamase.
Papp-Wallace KM et al.
Antibiotics (basel, Switzerland), 2023
Exploring the Role of the Ω-Loop in the Evolution of Ceftazidime Resistance in the PenA β-Lactamase from Burkholderia multivorans, an Important Cystic Fibrosis Pathogen.
Papp-Wallace KM et al.
Antimicrobial Agents and Chemotherapy, 2017
The tandem repeats enabling reversible switching between the two phases of β-lactamase substrate spectrum.
Yi H et al.
Plos Genetics, 2014
Structures of SHV-1 β-lactamase with penem and penam sulfone inhibitors that form cyclic intermediates stabilized by carbonyl conjugation.
Ke W et al.
Plos One, 2012
Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp.
Chen CC et al.
Protein Engineering, 1999
Site-directed mutagenesis of glutamate 166 in two beta-lactamases. Kinetic and molecular modeling studies.
Guillaume G et al.
The Journal of Biological Chemistry, 1997
Structural basis of extended spectrum TEM beta-lactamases. Crystallographic, kinetic, and mass spectrometric investigations of enzyme mutants.
Maveyraud L et al.
The Journal of Biological Chemistry, 1996
Select a paper to view details