Varaico: Literature-Extracted Genetic Variants

Gene:TOP1
Variant:p.F240I
Back to variants list

TOP1

NM_003286.4:p.F240I

Associated Papers

Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes.

Saha LK et al.

Nature Communications, 2023

37024461 (PubMed )
Supplement: 41467_2023_37498_MOESM1_ESM.pdf

Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.

Mabb AM et al.

Plos One, 2016

Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality.

Losasso C et al.

The Journal of Biological Chemistry, 2007

Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity.

Fiorani P et al.

Molecular Pharmacology, 1999

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."