Varaico: Literature-Extracted Genetic Variants

Gene:TOP1
Variant:p.G503S
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TOP1

NM_003286.4:p.G503S

Associated Papers

Mechanism of action of non-camptothecin inhibitor Genz-644282 in topoisomerase I inhibition.

Nishida M et al.

Communications Biology, 2022

New Topoisomerase I mutations are associated with resistance to camptothecin.

Gongora C et al.

Molecular Cancer, 2011

Topoisomerase I gene mutations at F270 in the large subunit and N184 in the small subunit contribute to the resistance mechanism of the unicellular parasite Leishmania donovani towards 3,3'-diindolylmethane.

Roy A et al.

Antimicrobial Agents and Chemotherapy, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."