Varaico: Literature-Extracted Genetic Variants

Gene:TOP2A
Variant:p.D48N
Back to variants list

TOP2A

NM_001067.4:p.D48N

Associated Papers

DNA Topoisomerase II Mutations in Cancer: Structural Impact and Drug Response in High-grade Serous Ovarian Carcinoma.

Mazzoleni V et al.

Journal of Molecular Biology, 2025

Modeling allosteric mechanisms of eukaryotic type II topoisomerases.

Evoli S et al.

Biophysical Journal, 2024

Modeling Allosteric Mechanisms of Eukaryotic Type II Topoisomerases.

Evoli S et al.

Biorxiv : the Preprint Server for Biology, 2024

A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193.

Ling EM et al.

Structure (london, England : 1993), 2022

A mutation in human topoisomerase II alpha whose expression is lethal in DNA repair-deficient yeast cells.

Walker JV et al.

The Journal of Biological Chemistry, 2004

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."