Associated Papers
The SMC5/SMC6 complex is critical for resolving R-loop-induced transcription-replication conflicts.
Wu T et al.
Nucleic Acids Research, 2026
Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability.
Erdinc D et al.
Embo Molecular Medicine, 2023
37013609 (PubMed )
Supplement: EMMM-15-e16775-s003.pdf
Top3α is the replicative topoisomerase in mitochondrial DNA replication.
Hangas A et al.
Nucleic Acids Research, 2022
Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.
Nicholls TJ et al.
Molecular Cell, 2018
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