Associated Papers
An autism spectrum disorder mutation in Topoisomerase 3β causes accumulation of covalent mRNA intermediates by disrupting metal binding within the zinc finger domain.
Warrick JE et al.
Nucleic Acids Research, 2025
An autism spectrum disorder mutation in Topoisomerase 3β causes accumulation of covalent mRNA intermediates by disrupting metal binding within the zinc finger domain.
Warrick JE et al.
Biorxiv : the Preprint Server for Biology, 2025
Structural insights into human topoisomerase 3β DNA and RNA catalysis and nucleic acid gate dynamics.
Yang X et al.
Nature Communications, 2025
Structural and biochemical basis for DNA and RNA catalysis by human Topoisomerase 3β.
Yang X et al.
Nature Communications, 2022
TDRD3 promotes DHX9 chromatin recruitment and R-loop resolution.
Yuan W et al.
Nucleic Acids Research, 2021
Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation.
Xu D et al.
Nature Neuroscience, 2013
Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders.
Stoll G et al.
Nature Neuroscience, 2013
Unraveling the Role of Topoisomerase 3β (TOP3B) in mRNA Translation and Human Disease.
Warrick JE et al.
Wiley Interdisciplinary Reviews. Rna, 0
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