Varaico: Literature-Extracted Genetic Variants

Gene:TOPBP1
Variant:p.R1314Q
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TOPBP1

NM_007027.4:p.R1314Q

Associated Papers

Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates.

Egger T et al.

Cell Reports, 2024

CK2 kinase-mediated PHF8 phosphorylation controls TopBP1 stability to regulate DNA replication.

Feng H et al.

Nucleic Acids Research, 2020

TOPBP1Dpb11 plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1Rad9.

Liu Y et al.

The Journal of Cell Biology, 2017

Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control.

Leung CC et al.

The Journal of Biological Chemistry, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."