Varaico: Literature-Extracted Genetic Variants

Gene:TOPBP1
Variant:p.L201H
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TOPBP1

NM_007027.4:p.L201H

Associated Papers

A cell cycle-independent mode of the Rad9-Dpb11 interaction is induced by DNA damage.

di Cicco G et al.

Scientific Reports, 2017

28912563 (PubMed )
Supplement: 41598_2017_11937_MOESM1_ESM.pdf

Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment.

Pfander B et al.

The Embo Journal, 2011

21946560 (PubMed )
Supplement: emboj2011345s1.pdf

Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint.

Puddu F et al.

Molecular and Cellular Biology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."