Varaico: Literature-Extracted Genetic Variants

Gene:TOPBP1
Variant:p.K155E
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TOPBP1

NM_007027.4:p.K155E

Associated Papers

The CIP2A-TOPBP1 axis facilitates mitotic DNA repair via MiDAS and MMEJ.

Martin PR et al.

Nature Communications, 2025

Biochemical analysis of TOPBP1 oligomerization.

Kim A et al.

Dna Repair, 2020

Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint.

Bigot N et al.

Elife, 2019

BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands.

Day M et al.

Elife, 2018

Regulation of DNA replication through Sld3-Dpb11 interaction is conserved from yeast to humans.

Boos D et al.

Current Biology : Cb, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."