Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.D393fs
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TP53

NM_000546.6:p.D393fs

Associated Papers

Identification of high-risk signatures and therapeutic targets through molecular characterization and immune profiling of TP53-mutant breast cancer.

Paulino PJIV et al.

Journal, Genetic Engineering & Biotechnology, 2025

41386839 (PubMed )
Supplement: mmc5.xlsx › Table_S3

Pan-cancer molecular analysis of EGFR large fragment deletion in the Asian population.

Pu J et al.

Cancer Medicine, 2023

36622089 (PubMed )
Supplement: CAM4-12-8083-s002.xlsx › Sheet1

Upfront Next Generation Sequencing in Non-Small Cell Lung Cancer.

Kuang S et al.

Current Oncology (toronto, Ont.), 2022

35877212 (PubMed )
Supplement: curroncol-29-00352-s001.zip › LUNGS1_16_june_2022_supplemental_2_variants_no_code.pdf

Cancer-derived C-terminus-extended p53 mutation confers dominant-negative effect on its wild-type counterpart.

Huang S et al.

Journal of Molecular Cell Biology, 2022

34918105 (PubMed )
Supplement: mjab078_supplemental_file.pdf

Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mutant p53-associated features.

Benor G et al.

Molecular Oncology, 2020

32484602 (PubMed )
Supplement: MOL2-14-1640-s004.xlsx › Sheet1

Phase and context shape the function of composite oncogenic mutations.

Gorelick AN et al.

Nature, 2020

32461694 (PubMed )
Supplement: NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx › Table_S2._Composite_mutations

From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.

Quinn EA et al.

Cold Spring Harbor Molecular Case Studies, 2019

30886117 (PubMed )
Supplement: supp_mcs.a003921_Supplemental_Table_1a.xlsx › S_Table1a._TP53_in_ClinVar
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."