Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.R379fs
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TP53

NM_000546.6:p.R379fs

Associated Papers

Ultrasensitive profiling of UV-induced mutations identifies thousands of subclinical facial tumors in tuberous sclerosis complex.

Klonowska K et al.

The Journal of Clinical Investigation, 2022

35358092 (PubMed )
Supplement: jci-132-155858-s188.xlsx › Supplemental_Table_5.2.

Cancer-derived C-terminus-extended p53 mutation confers dominant-negative effect on its wild-type counterpart.

Huang S et al.

Journal of Molecular Cell Biology, 2022

34918105 (PubMed )
Supplement: mjab078_supplemental_file.pdf

TP53 somatic mutations are associated with poor survival in non-small cell lung cancer patients who undergo immunotherapy.

Zhao L et al.

Aging, 2020

32694238 (PubMed )
Supplement: aging-12-103502-s001..xlsx › 67_patients_with_truncating_mut
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."