Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.T377A
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TP53

NM_000546.6:p.T377A

Associated Papers

Deciphering the acetylation code of p53 in transcription regulation and tumor suppression.

Xia Z et al.

Oncogene, 2022

TP53_PROF: a machine learning model to predict impact of missense mutations in TP53.

Ben-Cohen G et al.

Briefings in Bioinformatics, 2022

35043155 (PubMed )
Supplement: supplementary_table_s1_bbab524.xlsx › S1B._Negative_Set

Pathogenic genetic variants from highly connected cancer susceptibility genes confer the loss of structural stability.

Reza MN et al.

Scientific Reports, 2021

34584144 (PubMed )
Supplement: 41598_2021_98547_MOESM1_ESM.zip › Supplementary_files-5-8-21 › Supplementary_file_3.xlsx › Sheet1

From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.

Quinn EA et al.

Cold Spring Harbor Molecular Case Studies, 2019

30886117 (PubMed )
Supplement: supp_mcs.a003921_Supplemental_Table_1a.xlsx › S_Table1a._TP53_in_ClinVar

p53 Acetylation: Regulation and Consequences.

Reed SM et al.

Cancers, 2014

Potential conformational heterogeneity of p53 bound to S100B(ββ).

McDowell C et al.

Journal of Molecular Biology, 2013

Inhibition of p53 transcriptional activity by the S100B calcium-binding protein.

Lin J et al.

The Journal of Biological Chemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."