Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.K372Q
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TP53

NM_000546.6:p.K372Q

Associated Papers

TP53 variant clusters stratify phenotypic diversity in germline carriers and reveal an osteosarcoma-prone subgroup.

Fischer NW et al.

Nature Communications, 2025

41022739 (PubMed )
Supplement: 41467_2025_63528_MOESM7_ESM.xlsx › Sheet1

Alternatively mechanistic insights into acetylation in p53-mediated transcriptional regulation of cancer cell-intrinsic PD-1.

Wen J et al.

Fundamental Research, 2023

Transcription-independent functions of p53 in DNA repair pathway selection.

Wang YH et al.

Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology, 2023

TP53_PROF: a machine learning model to predict impact of missense mutations in TP53.

Ben-Cohen G et al.

Briefings in Bioinformatics, 2022

35043155 (PubMed )
Supplement: supplementary_table_s1_bbab524.xlsx › S1B._Negative_Set

Mutation screening of TP53, CHEK2 and BRCA genes in patients at high risk for hereditary breast and ovarian cancer (HBOC) in Brazil.

Cipriano NM et al.

Breast Cancer (tokyo, Japan), 2019

BRCA1 and BRCA2 sequence variations detected with next-generation sequencing in patients with premature ovarian insufficiency.

Yılmaz NK et al.

Journal of the Turkish German Gynecological Association, 2016

The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain.

Laptenko O et al.

Molecular Cell, 2015

The nucleolar protein Myb-binding protein 1A (MYBBP1A) enhances p53 tetramerization and acetylation in response to nucleolar disruption.

Ono W et al.

The Journal of Biological Chemistry, 2014

Kinetics of repression by modified p53 on the PDGF beta-receptor promoter.

Yang W et al.

International Journal of Cancer, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."