Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.K357Q
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TP53

NM_000546.6:p.K357Q

Associated Papers

TP53 variant clusters stratify phenotypic diversity in germline carriers and reveal an osteosarcoma-prone subgroup.

Fischer NW et al.

Nature Communications, 2025

41022739 (PubMed )
Supplement: 41467_2025_63528_MOESM7_ESM.xlsx › Sheet1

Targeting the MDM2-p53 Interaction with Siremadlin: A Promising Therapeutic Strategy for Treating TP53 Wild-Type Chronic Lymphocytic Leukemia.

Aptullahoglu E et al.

Cancers, 2025

TP53_PROF: a machine learning model to predict impact of missense mutations in TP53.

Ben-Cohen G et al.

Briefings in Bioinformatics, 2022

35043155 (PubMed )
Supplement: supplementary_table_s1_bbab524.xlsx › S1B._Negative_Set

Lysines in the tetramerization domain of p53 selectively modulate G1 arrest.

Beckerman R et al.

Cell Cycle (georgetown, Tex.), 2016

Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies.

Goldstein I et al.

Cancer Gene Therapy, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."