Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.Q331fs
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TP53

NM_000546.6:p.Q331fs

Associated Papers

Evaluation of non-canonical p53 functions in DNA replication and recombination for variant classification.

Jansche R et al.

Cell Death & Disease, 2026

Determinants of long-term response to patritumab deruxtecan in breast cancer patient-derived xenografts.

Òdena A et al.

Npj Precision Oncology, 2025

41272064 (PubMed )
Supplement: 41698_2025_1172_MOESM1_ESM.pdf

Single cell multi-omics reveal intra-cell-line heterogeneity across human cancer cell lines.

Zhu Q et al.

Nature Communications, 2023

38071219 (PubMed )
Supplement: 41467_2023_43991_MOESM2_ESM.pdf

TP53 germline pathogenic variants in modern humans were likely originated during recent human history.

Kou SH et al.

Nar Cancer, 2023

37304756 (PubMed )
Supplement: zcad025_supplemental_files.zip › Supplementary_Table_2.xlsx › PVs

High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer.

Palafox M et al.

Nature Communications, 2022

36071033 (PubMed )
Supplement: 41467_2022_32828_MOESM4_ESM.xlsx › Fig_2A_and_Table_S4

Targeted next generation sequencing of circulating tumor DNA provides prognostic information for management in breast cancer patients.

Shim H et al.

Annals of Translational Medicine, 2022

Proteasome Inhibition Overcomes ALK-TKI Resistance in ALK-Rearranged/TP53-Mutant NSCLC via Noxa Expression.

Tanimoto A et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2021

33310890 (PubMed )
Supplement: 10780432ccr202853-sup-247837_2_supp_6752777_qkgmhg.xlsx › Table_S1

Identification of relevant genetic alterations in cancer using topological data analysis.

Rabadán R et al.

Nature Communications, 2020

32732999 (PubMed )
Supplement: 41467_2020_17659_MOESM3_ESM.xls › TableS1

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.

Bolli N et al.

Leukemia, 2018

29789651 (PubMed )
Supplement: 41375_2018_37_MOESM14_ESM.xlsx › supp_Table1

Pancreatic Juice Mutation Concentrations Can Help Predict the Grade of Dysplasia in Patients Undergoing Pancreatic Surveillance.

Suenaga M et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2018

Mutations driving CLL and their evolution in progression and relapse.

Landau DA et al.

Nature, 2015

26466571 (PubMed )
Supplement: NIHMS715090-supplement-Supplementary_Table_10.xlsx › deep_seq_evolving_clone_TP1

XMAn: a Homo sapiens mutated-peptide database for the MS analysis of cancerous cell states.

Yang X et al.

Journal of Proteome Research, 2014

Patterns and Biologic Features of p53 Mutation Types in Korean Breast Cancer Patients.

Kim HW et al.

Journal of Breast Cancer, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."