Associated Papers
TP53 mutation heterogeneity reveals distinct prognoses in mantle cell lymphoma.
Liu S et al.
Annals of Hematology, 2026
TP53 variant clusters stratify phenotypic diversity in germline carriers and reveal an osteosarcoma-prone subgroup.
Fischer NW et al.
Nature Communications, 2025
Suppression of stress granule formation is a vulnerability imposed by mutant p53.
Thoenen E et al.
Nature Communications, 2025
Comprehensive classification of TP53 somatic missense variants based on their impact on p53 structural stability.
Tam B et al.
Briefings in Bioinformatics, 2024
Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival.
Li H et al.
Cell Reports, 2022
Immunohistochemical expression of HIF-1α, IDH1 and TP53: Prognostic profile of Moroccan patients with diffuse glioma.
Sfifou F et al.
Journal of Chemical Neuroanatomy, 2022
Identification of relevant genetic alterations in cancer using topological data analysis.
Rabadán R et al.
Nature Communications, 2020
Computational Analysis of IDH1, IDH2, and TP53 Mutations in Low-Grade Gliomas Including Oligodendrogliomas and Astrocytomas.
Bendahou MA et al.
Cancer Informatics, 2020
Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.
Holehouse AS et al.
Plos One, 2015
Proteome-wide analysis of human disease mutations in short linear motifs: neglected players in cancer?
Uyar B et al.
Molecular Biosystems, 2014
Nuclear and cytoplasmic p53 suppress cell invasion by inhibiting respiratory complex-I activity via Bcl-2 family proteins.
Kim EM et al.
Oncotarget, 2014
TP53 mutations in human cancer: database reassessment and prospects for the next decade.
Leroy B et al.
Human Mutation, 2014
Gain of function of mutant p53 by coaggregation with multiple tumor suppressors.
Xu J et al.
Nature Chemical Biology, 2011
Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation.
Migliorini D et al.
The Journal of Biological Chemistry, 2002
A role for Hsc70 in regulating nucleocytoplasmic transport of a temperature-sensitive p53 (p53Val-135).
Akakura S et al.
The Journal of Biological Chemistry, 2001
MDM2-dependent ubiquitination of nuclear and cytoplasmic P53.
Yu ZK et al.
Oncogene, 2000
A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain.
Liang SH et al.
The Journal of Biological Chemistry, 1999
Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein.
Liang SH et al.
The Journal of Biological Chemistry, 1998