Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.P301S
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TP53

NM_000546.6:p.P301S

Associated Papers

TP53 mutation heterogeneity reveals distinct prognoses in mantle cell lymphoma.

Liu S et al.

Annals of Hematology, 2026

41559357 (PubMed )
Supplement: 277_2026_6771_MOESM2_ESM.xlsx › TableS3

Mutant MAPT Induces rDNA Transcriptional Hyperactivation and Nucleolar Stress in Cellular Models.

Muhammad Z et al.

Research Square, 2025

Understanding Tau pathology: Insights from animal models.

Zhang H et al.

Zoological Research, 2025

Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.

Carling GK et al.

Neuron, 2024

Scalable approaches for generating, validating and incorporating data from high-throughput functional assays to improve clinical variant classification.

Padigepati SR et al.

Human Genetics, 2024

39085601 (PubMed )
Supplement: 439_2024_2691_MOESM2_ESM.xlsx › TP53

Comprehensive classification of TP53 somatic missense variants based on their impact on p53 structural stability.

Tam B et al.

Briefings in Bioinformatics, 2024

39140857 (PubMed )
Supplement: table_s1_bbae400.xlsx › Sheet1

Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.

Carling GK et al.

Biorxiv : the Preprint Server for Biology, 2024

Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy.

Williams T et al.

Acta Neuropathologica Communications, 2023

Lack of ApoE inhibits ADan amyloidosis in a mouse model of familial Danish dementia.

Fernandez A et al.

The Journal of Biological Chemistry, 2023

Stepwise correlation of TP53 mutations from pancreaticobiliary maljunction to gallbladder carcinoma: a retrospective study.

Kawakami S et al.

Bmc Cancer, 2021

34798839 (PubMed )
Supplement: 12885_2021_9000_MOESM2_ESM.pdf

Activated cofilin exacerbates tau pathology by impairing tau-mediated microtubule dynamics.

Woo JA et al.

Communications Biology, 2019

Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.

Wong SQ et al.

British Journal of Cancer, 2015

25742471 (PubMed )
Supplement: bjc201580x7.xls › Supp_Table_3

Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Holehouse AS et al.

Plos One, 2015

26659599 (PubMed )
Supplement: pone.0144692.s002.xlsx › suppTable_2.txt

Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts.

Vardarajan B et al.

Molecular Neurodegeneration, 2013

Interleukin-18 increases expression of kinases involved in tau phosphorylation in SH-SY5Y neuroblastoma cells.

Ojala JO et al.

Journal of Neuroimmunology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."