Associated Papers
Targeting p53 pathways: mechanisms, structures, and advances in therapy.
Wang H et al.
Signal Transduction and Targeted Therapy, 2023
TP53_PROF: a machine learning model to predict impact of missense mutations in TP53.
Ben-Cohen G et al.
Briefings in Bioinformatics, 2022
35043155 (PubMed )
Supplement: supplementary_table_s1_bbab524.xlsx › S1B._Negative_Set
Finding driver mutations in cancer: Elucidating the role of background mutational processes.
Brown AL et al.
Plos Computational Biology, 2019
31034466 (PubMed )
Supplement: pcbi.1006981.s010.xlsx › final_benchmark
Structure and Function of p53-DNA Complexes with Inactivation and Rescue Mutations: A Molecular Dynamics Simulation Study.
Kamaraj B et al.
Plos One, 2015
Heterogeneous Mechanisms of Secondary Resistance and Clonal Selection in Sarcoma during Treatment with Nutlin.
Laroche A et al.
Plos One, 2015
QM-MM simulations on p53-DNA complex: a study of hot spot and rescue mutants.
Koulgi S et al.
Journal of Molecular Modeling, 2013
Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions.
Eldar A et al.
Nucleic Acids Research, 2013
Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue.
Wallentine BD et al.
Acta Crystallographica. Section D, Biological Crystallography, 2013
Molecular mechanisms of functional rescue mediated by P53 tumor suppressor mutations.
Tan YH et al.
Biophysical Chemistry, 2009
Structure-function-rescue: the diverse nature of common p53 cancer mutants.
Joerger AC et al.
Oncogene, 2007
Factors governing loss and rescue of DNA binding upon single and double mutations in the p53 core domain.
Wright JD et al.
Nucleic Acids Research, 2002
Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations.
Brachmann RK et al.
The Embo Journal, 1998
Select a paper to view details