Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.S261Splc
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TP53

NM_000546.6:p.S261Splc

Associated Papers

Deep Sequencing Reveals Novel Mutations in Androgen Receptor-Related Genes in Prostate Cancer.

Pedroza-Torres A et al.

International Journal of Molecular Sciences, 2025

41009328 (PubMed )
Supplement: ijms-26-08758-s001.zip › Suppl_Table_1.xlsx › Hoja1

Feasibility of long-read sequencing to identify molecular alterations in an Indonesian cohort of locally advanced to advanced nasopharyngeal cancer.

Handoko et al.

Scientific Reports, 2025

40594369 (PubMed )
Supplement: 41598_2025_6096_MOESM8_ESM.zip › Supp_Data_6 › S1_SNV.xlsx › s1_TP53

Genomic instability in ovarian cancer: Through the lens of single nucleotide polymorphisms.

Canchi Sistla H et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2025

Molecular insights into TP53 mutation (p. Arg267Trp) and its connection to Choroid Plexus Carcinomas and Li-Fraumeni Syndrome.

Abduljaleel Z

Genes & Genomics, 2024

TP53 germline pathogenic variants in modern humans were likely originated during recent human history.

Kou SH et al.

Nar Cancer, 2023

37304756 (PubMed )
Supplement: zcad025_supplemental_files.zip › Supplementary_Table_2.xlsx › BVs

Mutational landscape of gastric adenocarcinoma in Latin America: A genetic approach for precision medicine.

Cerrato-Izaguirre D et al.

Genes & Diseases, 2022

In search of TP53 mutational hot spots for Li-Fraumeni syndrome in Asian populations.

Lo Piccolo L et al.

Tropical Medicine & International Health : Tm & Ih, 2021

Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.

Doffe F et al.

Cell Death and Differentiation, 2021

33257846 (PubMed )
Supplement: 41418_2020_672_MOESM3_ESM.xlsx › Table_S2a

Prevalence of germline TP53 variants among early-onset breast cancer patients from Polish population.

Rogoża-Janiszewska E et al.

Breast Cancer (tokyo, Japan), 2021

Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal cancer patients.

Manoharan V et al.

Bmc Cancer, 2020

Nucleotide variants and protein expression of TP53 in a Sri Lankan cohort of patients with head and neck cancer.

Manoharan V et al.

Molecular Medicine Reports, 2019

Identification and characterization of TP53 gene Allele Dropout in Li-Fraumeni syndrome and Oral cancer cohorts.

Haque MM et al.

Scientific Reports, 2018

TP53 Mutation Status of Tubo-ovarian and Peritoneal High-grade Serous Carcinoma with a Wild-type p53 Immunostaining Pattern.

Na K et al.

Anticancer Research, 2017

Somatic TP53 Mutations in the Era of Genome Sequencing.

Hainaut P et al.

Cold Spring Harbor Perspectives in Medicine, 2016

Screening for germline BRCA1, BRCA2, TP53 and CHEK2 mutations in families at-risk for hereditary breast cancer identified in a population-based study from Southern Brazil.

Palmero EI et al.

Genetics and Molecular Biology, 2016

Germline TP53 mutational spectrum in French Canadians with breast cancer.

Arcand SL et al.

Bmc Medical Genetics, 2015

Epistatic interaction of Arg72Pro TP53 and -710 C/T VEGFR1 polymorphisms in breast cancer: predisposition and survival.

Rodrigues P et al.

Molecular and Cellular Biochemistry, 2013

Detection of p53 common intron polymorphisms in patients with gastritis lesions from Iran.

Najjar Sadeghi R et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2013

Association of intron and exon polymorphisms of p53 gene in Iranian patients with gastritis.

Najjar Sadeghi R et al.

Gastroenterology and Hepatology From Bed to Bench, 2013

Innate immunity and non-Hodgkin's lymphoma (NHL) related genes in a nested case-control study for gastric cancer risk.

Park SK et al.

Plos One, 2012

23028900 (PubMed )
Supplement: pone.0045274.s001.xlsx › NHL

TP53 mutations in human cancers: origins, consequences, and clinical use.

Olivier M et al.

Cold Spring Harbor Perspectives in Biology, 2010

Common genetic variation in TP53 and risk of human papillomavirus persistence and progression to CIN3/cancer revisited.

Koshiol J et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2009

Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity.

Lan Q et al.

Carcinogenesis, 2009

Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population.

Yamada H et al.

Carcinogenesis, 2007

Genetic variation in TP53 and risk of breast cancer in a population-based case control study.

Sprague BL et al.

Carcinogenesis, 2007

Common genetic variation in TP53 is associated with lung cancer risk and prognosis in African Americans and somatic mutations in lung tumors.

Mechanic LE et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2007

17301252 (PubMed )
Supplement: 10559965epi060790-sup-cebp_2-1-07_mechanic_et_al.pdf
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