Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.H233N
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TP53

NM_000546.6:p.H233N

Associated Papers

TP53 variant clusters stratify phenotypic diversity in germline carriers and reveal an osteosarcoma-prone subgroup.

Fischer NW et al.

Nature Communications, 2025

41022739 (PubMed )
Supplement: 41467_2025_63528_MOESM7_ESM.xlsx › Sheet1

Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.

Funk JS et al.

Nature Genetics, 2025

39774325 (PubMed )
Supplement: 41588_2024_2039_MOESM5_ESM.xlsx › SuppFig6

TP53_PROF: a machine learning model to predict impact of missense mutations in TP53.

Ben-Cohen G et al.

Briefings in Bioinformatics, 2022

35043155 (PubMed )
Supplement: supplementary_table_s1_bbab524.xlsx › S1B._Negative_Set

Clinicopathological and molecular characteristics of patients with hypermutant lung cancer: A retrospective cohort study.

Zhang H et al.

Oncology Letters, 2021

33692861 (PubMed )
Supplement: Supplementary_Data.pdf

Tissue-specific microRNA expression alters cancer susceptibility conferred by a TP53 noncoding variant.

Deng Q et al.

Nature Communications, 2019

31699989 (PubMed )
Supplement: 41467_2019_13002_MOESM1_ESM.pdf

Validation and utilisation of high-coverage next-generation sequencing to deliver the pharmacological audit trail.

Ong M et al.

British Journal of Cancer, 2014

Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein.

Ahn J et al.

Cell Cycle (georgetown, Tex.), 2009

Functional protein microarrays for parallel characterisation of p53 mutants.

Boutell JM et al.

Proteomics, 2004

Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation.

Malcikova J et al.

Biological Chemistry, 0

Higher TP53 somatic mutation prevalence from liquid biopsy analysis in ever smoker non-small-cell lung cancer patients.

Erdem HB et al.

Mutation Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."