Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.S227P
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TP53

NM_000546.6:p.S227P

Associated Papers

Correlation analysis of TP53 missense mutations and p53 protein expression patterns in endometrial carcinoma.

Yang Y et al.

Human Pathology, 2026

Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.

Funk JS et al.

Nature Genetics, 2025

39774325 (PubMed )
Supplement: 41588_2024_2039_MOESM5_ESM.xlsx › SuppFig6

Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

G V et al.

Frontiers in Genetics, 2022

36561320 (PubMed )
Supplement: Table2.xlsx › EGFR

The Mutational Landscape of Metastatic Castration-sensitive Prostate Cancer: The Spectrum Theory Revisited.

Deek MP et al.

European Urology, 2021

33419682 (PubMed )
Supplement: NIHMS1793749-supplement-20.xlsx › Sheet1

Clinicopathological and molecular characteristics of patients with hypermutant lung cancer: A retrospective cohort study.

Zhang H et al.

Oncology Letters, 2021

33692861 (PubMed )
Supplement: Supplementary_Data.pdf

Somatic Mutation Profiles Revealed by Next Generation Sequencing (NGS) in 39 Chinese Hepatocellular Carcinoma Patients.

Ke L et al.

Frontiers in Molecular Biosciences, 2021

35118119 (PubMed )
Supplement: Table6.xlsx › Sheet1

Identification of relevant genetic alterations in cancer using topological data analysis.

Rabadán R et al.

Nature Communications, 2020

32732999 (PubMed )
Supplement: 41467_2020_17659_MOESM3_ESM.xls › TableS1

On the complexity measures of mutation hotspots in human TP53 protein.

Ding Y et al.

Chaos (woodbury, N.y.), 2020

Metabolic Pathways Enhancement Confers Poor Prognosis in p53 Exon Mutant Hepatocellular Carcinoma.

Chen PM et al.

Cancer Informatics, 2020

Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer.

Kwon SM et al.

Scientific Reports, 2019

31729408 (PubMed )
Supplement: 41598_2019_52578_MOESM2_ESM.pdf

Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies.

Xiu J et al.

Oncotarget, 2016

26933808 (PubMed )
Supplement: oncotarget-07-21556-s001.pdf

"p53 mutation spectrum and its role in prognosis of oral cancer patients: A study from Gujarat, West India".

Singh RD et al.

Mutation Research, 2016

Mutational and gene fusion analyses of primary large cell and large cell neuroendocrine lung cancer.

Karlsson A et al.

Oncotarget, 2015

26124082 (PubMed )
Supplement: oncotarget-06-22028-s003.xlsx › Variants_in_Seidel

Human catalase, its polymorphisms, regulation and changes of its activity in different diseases.

Kodydková J et al.

Folia Biologica, 2014

A comprehensive study of TP53 mutations in chronic lymphocytic leukemia: Analysis of 1287 diagnostic and 1148 follow-up CLL samples.

Pekova S et al.

Leukemia Research, 2011

Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70.

Singh LR et al.

Plos Genetics, 2010

20066033 (PubMed )
Supplement: pgen.1000807.s006.pdf

The screening of the second-site suppressor mutations of the common p53 mutants.

Otsuka K et al.

International Journal of Cancer, 2007

Mutation of p53 Gene and Its Correlation with the Clinical Outcome in Dogs with Lymphoma.

Koshino A et al.

Journal of Veterinary Internal Medicine, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."