Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.P223A
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TP53

NM_000546.6:p.P223A

Associated Papers

Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.

Funk JS et al.

Nature Genetics, 2025

39774325 (PubMed )
Supplement: 41588_2024_2039_MOESM5_ESM.xlsx › SuppFig6

Comprehensive classification of TP53 somatic missense variants based on their impact on p53 structural stability.

Tam B et al.

Briefings in Bioinformatics, 2024

39140857 (PubMed )
Supplement: table_s1_bbae400.xlsx › Sheet1

Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma.

Wong K et al.

Nature Communications, 2019

30664638 (PubMed )
Supplement: 41467_2018_8081_MOESM5_ESM.xlsx › Canine

Dynamics of multiple resistance mechanisms in plasma DNA during EGFR-targeted therapies in non-small cell lung cancer.

Tsui DWY et al.

Embo Molecular Medicine, 2018

29848757 (PubMed )
Supplement: EMMM-10-e7945-s001.pdf

Comparison of the human and worm p53 structures suggests a way for enhancing stability.

Pan Y et al.

Biochemistry, 2006

Isolation of temperature-sensitive p53 mutations from a comprehensive missense mutation library.

Shiraishi K et al.

The Journal of Biological Chemistry, 2004

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas.

Kurose K et al.

Nature Genetics, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."