Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.R209S
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TP53

NM_000546.6:p.R209S

Associated Papers

TP53 minigene analysis of 161 sequence changes provides evidence for role of spatial constraint and regulatory elements on variant-induced splicing impact.

Canson DM et al.

Npj Genomic Medicine, 2025

40341019 (PubMed )
Supplement: 41525_2025_498_MOESM2_ESM.xlsx › Data_S2

Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.

Funk JS et al.

Nature Genetics, 2025

39774325 (PubMed )
Supplement: 41588_2024_2039_MOESM5_ESM.xlsx › SuppFig6

Comprehensive classification of TP53 somatic missense variants based on their impact on p53 structural stability.

Tam B et al.

Briefings in Bioinformatics, 2024

Validation of p53 Immunohistochemistry (PAb240 Clone) in Canine Tumors with Next-Generation Sequencing (NGS) Analysis.

Brunetti B et al.

Animals : an Open Access Journal From Mdpi, 2023

Genetic mutation profile of Chinese HER2-positive breast cancers and genetic predictors of responses to Neoadjuvant anti-HER2 therapy.

Li K et al.

Breast Cancer Research and Treatment, 2020

A quantitative model to predict pathogenicity of missense variants in the TP53 gene.

Fortuno C et al.

Human Mutation, 2019

Genomic Assessment of Blitz Nevi Suggests Classification as a Subset of Blue Nevus Rather Than Spitz Nevus: Clinical, Histopathologic, and Molecular Analysis of 18 Cases.

Isales MC et al.

The American Journal of Dermatopathology, 2018

p53 mutations in classic and pleomorphic invasive lobular carcinoma of the breast.

Ercan C et al.

Cellular Oncology (dordrecht, Netherlands), 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."