Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.A189D
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TP53

NM_000546.6:p.A189D

Associated Papers

TP53 variant clusters stratify phenotypic diversity in germline carriers and reveal an osteosarcoma-prone subgroup.

Fischer NW et al.

Nature Communications, 2025

41022739 (PubMed )
Supplement: 41467_2025_63528_MOESM7_ESM.xlsx › Sheet1

Prognostic significance of circulating tumor DNA alterations in advanced renal cell carcinoma from SCRUM-Japan MONSTAR-SCREEN: a nationwide genomic profiling project.

Kato T et al.

British Journal of Cancer, 2025

40325148 (PubMed )
Supplement: 41416_2025_2985_MOESM2_ESM.xlsx › Supplementary_Table_S2

Structural and mechanistic diversity in p53-mediated regulation of organismal longevity across taxonomical orders.

Osbourne R et al.

Plos Computational Biology, 2025

Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.

Funk JS et al.

Nature Genetics, 2025

39774325 (PubMed )
Supplement: 41588_2024_2039_MOESM5_ESM.xlsx › SuppFig6

Variation characteristics and clinical significance of TP53 in patients with myeloid neoplasms.

Ma Q et al.

Hematology (amsterdam, Netherlands), 2024

Comprehensive classification of TP53 somatic missense variants based on their impact on p53 structural stability.

Tam B et al.

Briefings in Bioinformatics, 2024

39140857 (PubMed )
Supplement: table_s1_bbae400.xlsx › Sheet1

TP53 variants in p53 signatures and the clonality of STICs in RRSO samples.

Akahane T et al.

Journal of Gynecologic Oncology, 2022

35557033 (PubMed )
Supplement: jgo-33-e50-s001.xls › jgo-33-e50-s001

Usefulness of Circulating Tumor DNA in Identifying Somatic Mutations and Tracking Tumor Evolution in Patients With Non-small Cell Lung Cancer.

Roosan MR et al.

Chest, 2021

33878340 (PubMed )
Supplement: mmc1.pdf

High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants.

Razavi P et al.

Nature Medicine, 2019

31768066 (PubMed )
Supplement: NIHMS1541314-supplement-1541314_Sup_Tab.xlsx › Supplementary_Table_6

Missense mutations in the TP53 DNA-binding domain predict outcomes in patients with advanced oral cavity squamous cell carcinoma.

Lapke N et al.

Oncotarget, 2016

27283772 (PubMed )
Supplement: oncotarget-07-44194-s003.xlsx › Table_S2

Ultra-deep targeted sequencing of advanced oral squamous cell carcinoma identifies a mutation-based prognostic gene signature.

Chen SJ et al.

Oncotarget, 2015

25980437 (PubMed )
Supplement: oncotarget-06-18066-s004.xlsx › Sheet1

The genomic landscape of pediatric Ewing sarcoma.

Crompton BD et al.

Cancer Discovery, 2014

25186949 (PubMed )
Supplement: 21598290cd131037-sup-124608_2_supp_2613705_nwcnpj.xlsx › 16_MAF_cell_line

Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma.

Zhukova N et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."