Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.R174fs
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TP53

NM_000546.6:p.R174fs

Associated Papers

TP53 Inactivation Confers Resistance to the Menin Inhibitor Revumenib in Acute Myeloid Leukemia.

D'Souza J et al.

Biorxiv : the Preprint Server for Biology, 2025

Clinical significance of chromosomal integrity in gastric cancers.

Zhang R et al.

The International Journal of Biological Markers, 2022

35722719 (PubMed )
Supplement: sj-xlsx-1-jbm-10.1177_03936155221106217.xlsx › Sheet1

TP53 loss‑of‑function mutations reduce sensitivity of acute leukaemia to the curaxin CBL0137.

Forgione MO et al.

Oncology Reports, 2022

Metastatic pediatric sclerosing epithelioid fibrosarcoma.

Woods AD et al.

Cold Spring Harbor Molecular Case Studies, 2021

A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: Results from the CONKO-005 trial.

Hoyer K et al.

Ebiomedicine, 2021

33862582 (PubMed )
Supplement: mmc3.xlsx › S5

HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia.

Zhu G et al.

Nature Communications, 2021

33782403 (PubMed )
Supplement: 41467_2021_22095_MOESM1_ESM.pdf

Tumor DNA Mutations From Intraparenchymal Brain Metastases Are Detectable in CSF.

Cheok SK et al.

Jco Precision Oncology, 2021

Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis.

Kusnadi EP et al.

The Embo Journal, 2020

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors.

Smith AM et al.

Oncotarget, 2019

Characterization of frequently mutated cancer genes in Chinese breast tumors: a comparison of Chinese and TCGA cohorts.

Zhang G et al.

Annals of Translational Medicine, 2019

Mutational processes shape the landscape of TP53 mutations in human cancer.

Giacomelli AO et al.

Nature Genetics, 2018

30224644 (PubMed )
Supplement: NIHMS1501645-supplement-3.xlsx › Sheet1

Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions.

Brannon AR et al.

Genome Biology, 2014

25164765 (PubMed )
Supplement: 13059_2014_454_MOESM1_ESM.xlsx › Sheet1

Genomic and molecular characterization of esophageal squamous cell carcinoma.

Lin DC et al.

Nature Genetics, 2014

24686850 (PubMed )
Supplement: NIHMS573166-supplement-9.xlsx › Supplementary_Table_6
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."