Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.K139fs
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TP53

NM_000546.6:p.K139fs

Associated Papers

Simultaneous p53 and p16 Immunostaining for Molecular Subclassification of Head and Neck Squamous Cell Carcinomas.

Pakkanen P et al.

Head and Neck Pathology, 2024

De novo germline TP53 mutation in a pediatric patient with Li-Fraumeni syndrome and diffuse peritoneal mesothelioma.

Ortaköylü MY et al.

Pediatric Blood & Cancer, 2024

Mutations in the TP53, VEGFA, and CTH Genes as Key Molecular Markers for the Diagnosis of Glioblastoma.

Khalil SS et al.

Cureus, 2024

TP53 germline pathogenic variants in modern humans were likely originated during recent human history.

Kou SH et al.

Nar Cancer, 2023

37304756 (PubMed )
Supplement: zcad025_supplemental_files.zip › Supplementary_Table_2.xlsx › PVs

Pure and mixed clear cell carcinoma of the endometrium: A molecular and immunohistochemical analysis study.

Reijnen C et al.

Cancer Medicine, 2023

37081760 (PubMed )
Supplement: CAM4-12-12365-s001.pdf

Meta-analysis of commonly mutated genes in leptomeningeal carcinomatosis.

Congur I et al.

Peerj, 2023

37096065 (PubMed )
Supplement: peerj-11-15250-s005.xlsx › Mutation_Info

Molecular characteristics of young-onset colorectal cancer in Vietnamese patients.

Do MD et al.

Asia-pacific Journal of Clinical Oncology, 2022

35098669 (PubMed )
Supplement: supplement_1.xlsx › Sheet1

Gain of Function (GOF) Mutant p53 in Cancer-Current Therapeutic Approaches.

Roszkowska KA et al.

International Journal of Molecular Sciences, 2022

Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c).

Fiskus W et al.

Blood Cancer Journal, 2022

35017466 (PubMed )
Supplement: 41408_2021_603_MOESM1_ESM.pdf

Evaluation of the CRISPR/Cas9 directed mutant TP53 gene repairing effect in human prostate cancer cell line PC-3.

Batır MB et al.

Molecular Biology Reports, 2019

High Proportion of Potential Candidates for Immunotherapy in a Chilean Cohort of Gastric Cancer Patients: Results of the FORCE1 Study.

Cordova-Delgado M et al.

Cancers, 2019

31480291 (PubMed )
Supplement: cancers-11-01275-s001.zip › Supplementary_data_file_1.xlsx › DNA

Detection of ERBB2 (HER2) Gene Amplification Events in Cell-Free DNA and Response to Anti-HER2 Agents in a Large Asian Cancer Patient Cohort.

Lee J et al.

Frontiers in Oncology, 2019

31019892 (PubMed )
Supplement: Table_2.XLSX › Supplementary_Table_2

VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.

Lai Z et al.

Nucleic Acids Research, 2016

27060149 (PubMed )
Supplement: gkw227_Supplementary_Data.zip › nar-03544-met-k-2015-File003.xls › Suppl._Table_3

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nik-Zainal S et al.

Nature, 2016

27135926 (PubMed )
Supplement: NIHMS68344-supplement-Supplementary_Tables_1-21.zip › nature17676-s3 › Supplementary_Table_14.Driver.Events.By.Mutation.Type.01052015.v2.xlsx › Subs.indels

Analysis of TP53 mutation status in human cancer cell lines: a reassessment.

Leroy B et al.

Human Mutation, 2014

The impact of EGFR T790M mutations and BIM mRNA expression on outcome in patients with EGFR-mutant NSCLC treated with erlotinib or chemotherapy in the randomized phase III EURTAC trial.

Costa C et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2014

24493829 (PubMed )
Supplement: 10780432ccr132233-sup-ccr-13-2233tab1-9fig1-5.pdf

CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.

Oberst MD et al.

Mabs, 2014

25484061 (PubMed )
Supplement: kmab-06-06-975660-s001.zip › Supplementary_Figure_2.pdf

Mutational landscape and significance across 12 major cancer types.

Kandoth C et al.

Nature, 2013

24132290 (PubMed )
Supplement: 41586_2013_BFnature12634_MOESM82_ESM.zip › nature12634-s1 › Supplementary_Table_5.xlsx › S_Table_5

Exome sequencing reveals comprehensive genomic alterations across eight cancer cell lines.

Chang H et al.

Plos One, 2011

Analysis of p53 mutation status in human cancer cell lines: a paradigm for cell line cross-contamination.

Berglind H et al.

Cancer Biology & Therapy, 2008

Myelodysplastic Neoplasm with Biallelic TP53 Mutations Presenting with Myelofibrosis and CD42b Expression: A Case Report.

Li X et al.

Case Reports in Oncology, 0

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