Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.Q136insFs
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TP53

NM_000546.6:p.Q136insFs

Associated Papers

Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.

Funk JS et al.

Nature Genetics, 2025

39774325 (PubMed )
Supplement: 41588_2024_2039_MOESM12_ESM.xlsx › Fig7b_d

Variable characteristics overlooked in human K-562 leukemia cell lines with a common signature.

Kasai F et al.

Scientific Reports, 2024

38671192 (PubMed )
Supplement: 41598_2024_60271_MOESM1_ESM.pdf

Synthetic lethality between TP53 and ENDOD1.

Tang Z et al.

Nature Communications, 2022

35606358 (PubMed )
Supplement: 41467_2022_30311_MOESM1_ESM.pdf

Polymorphism of VDR Gene and the Sensitivity of Human Leukemia and Lymphoma Cells to Active Forms of Vitamin D.

Gleba JJ et al.

Cancers, 2022

Synergistic effects of PRIMA-1Met (APR-246) and 5-azacitidine in TP53-mutated myelodysplastic syndromes and acute myeloid leukemia.

Maslah N et al.

Haematologica, 2020

Dysfunction of the WT1-MEG3 signaling promotes AML leukemogenesis via p53-dependent and -independent pathways.

Lyu Y et al.

Leukemia, 2017

28400619 (PubMed )
Supplement: leu2017116x1.docx

A variant by any name: quantifying annotation discordance across tools and clinical databases.

Yen JL et al.

Genome Medicine, 2017

28122645 (PubMed )
Supplement: 13073_2016_396_MOESM1_ESM.xlsx › Table_S1

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nik-Zainal S et al.

Nature, 2016

27135926 (PubMed )
Supplement: NIHMS68344-supplement-Supplementary_Tables_1-21.zip › nature17676-s3 › Supplementary_Table_14.Driver.Events.By.Mutation.Type.01052015.v2.xlsx › Subs.indels

Dissecting Genomic Aberrations in Myeloproliferative Neoplasms by Multiplex-PCR and Next Generation Sequencing.

Kirschner MM et al.

Plos One, 2015

Illuminator, a desktop program for mutation detection using short-read clonal sequencing.

Carr IM et al.

Genomics, 2011

Analysis of p53 mutation status in human cancer cell lines: a paradigm for cell line cross-contamination.

Berglind H et al.

Cancer Biology & Therapy, 2008

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

Ikediobi ON et al.

Molecular Cancer Therapeutics, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."