Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.S20A
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TP53

NM_000546.6:p.S20A

Associated Papers

A quantitative, Bayesian-informed approach to gene-specific variant classification: Updated Expert Panel recommendations improve classification of TP53 germline variants for Li-Fraumeni syndrome.

Fortuno C et al.

Genome Medicine, 2025

41126324 (PubMed )
Supplement: 13073_2025_1536_MOESM2_ESM.xlsx › Table_S2

TP53_PROF: a machine learning model to predict impact of missense mutations in TP53.

Ben-Cohen G et al.

Briefings in Bioinformatics, 2022

35043155 (PubMed )
Supplement: supplementary_table_s1_bbab524.xlsx › S1B._Negative_Set

The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3.

Vaughan CA et al.

Nature Communications, 2021

Translational Control in p53 Expression: The Role of 5'-Terminal Region of p53 mRNA.

Swiatkowska A et al.

International Journal of Molecular Sciences, 2019

Structural and sequential context of p53: A review of experimental and theoretical evidence.

Saha T et al.

Progress in Biophysics and Molecular Biology, 2015

Mutant TP53 posttranslational modifications: challenges and opportunities.

Nguyen TA et al.

Human Mutation, 2014

ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres.

Thanasoula M et al.

The Embo Journal, 2012

Study of MDM2 binding to p53-analogues: affinity, helicity, and applicability to drug design.

Kalid O et al.

Journal of Chemical Information and Modeling, 2009

Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.

MacPherson D et al.

The Embo Journal, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."