Varaico: Literature-Extracted Genetic Variants

Gene:TPH2
Variant:p.S41Y
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TPH2

NM_173353.4:p.S41Y

Associated Papers

In silico analysis of the tryptophan hydroxylase 2 (TPH2) protein variants related to psychiatric disorders.

Pereira GRC et al.

Plos One, 2020

Association between gene polymorphism and depression in Parkinson's disease: A case-control study.

Zheng J et al.

Journal of the Neurological Sciences, 2017

Functional characterization of the S41Y (C2755A) polymorphism of tryptophan hydroxylase 2.

Carkaci-Salli N et al.

Journal of Neurochemistry, 2014

Genes in the serotonin pathway are associated with bipolar affective disorder in a Han Chinese population.

Xiang B et al.

Neuroscience Bulletin, 2014

A two-stage case-control association study between the tryptophan hydroxylase 2 (TPH2) gene and schizophrenia in a Japanese population.

Watanabe Y et al.

Schizophrenia Research, 2012

A detailed association analysis between the tryptophan hydroxylase 2 (TPH2) gene and autism spectrum disorders in a Japanese population.

Egawa J et al.

Psychiatry Research, 2012

Association analysis of the tryptophan hydroxylase 2 gene polymorphisms in patients with methamphetamine dependence/psychosis.

Kobayashi H et al.

Current Neuropharmacology, 2011

Targeting tryptophan hydroxylase 2 in affective disorder.

Popova NK et al.

Expert Opinion on Therapeutic Targets, 2010

Distribution of the C1473G polymorphism in tryptophan hydroxylase 2 gene in laboratory and wild mice.

Osipova DV et al.

Genes, Brain, and Behavior, 2010

Population-specific functional variant of the TPH2 gene 2755C>A polymorphism contributes risk association to major depression and anxiety in Chinese peripartum women.

Lin YM et al.

Archives of Women's Mental Health, 2009

Functional properties of missense variants of human tryptophan hydroxylase 2.

McKinney JA et al.

Human Mutation, 2009

Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response.

Peters EJ et al.

Pharmacogenetics and Genomics, 2009

Rhesus monkey tryptophan hydroxylase-2 coding region haplotypes affect mRNA stability.

Chen GL et al.

Neuroscience, 2008

A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression.

Murphy KL et al.

The Journal of Biological Chemistry, 2008

Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16.

Zhou Z et al.

Neuron, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."