Varaico: Literature-Extracted Genetic Variants

Gene:TPH2
Variant:p.I158N
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TPH2

NM_173353.4:p.I158N

Associated Papers

Genetics of suicide ideation. A role for inflammation and neuroplasticity?

Turiaco F et al.

European Archives of Psychiatry and Clinical Neuroscience, 2024

Tryptophan hydroxylase 2 as a therapeutic target for psychiatric disorders: focus on animal models.

Kulikova EA et al.

Expert Opinion on Therapeutic Targets, 2019

Serotonergic neurotransmission manipulation for the understanding of brain development and function: Learning from Tph2 genetic models.

Pratelli M et al.

Biochimie, 2019

The Interaction of TPH2 and 5-HT2A Polymorphisms on Major Depressive Disorder Susceptibility in a Chinese Han Population: A Case-Control Study.

Yang J et al.

Frontiers in Psychiatry, 2019

Interaction of tryptophan hydroxylase 2 gene and life events in susceptibility to major depression in a Chinese Han population.

Ma J et al.

Journal of Affective Disorders, 2015

TPH2 gene polymorphisms in the regulatory region are associated with paranoid schizophrenia in Northern Han Chinese.

Xu XM et al.

Genetics and Molecular Research : Gmr, 2014

The c.1460C>T polymorphism of MAO-A is associated with the risk of depression in postmenopausal women.

Słopień R et al.

Thescientificworldjournal, 2012

Targeting tryptophan hydroxylase 2 in affective disorder.

Popova NK et al.

Expert Opinion on Therapeutic Targets, 2010

TPH2 polymorphisms and expression in Prader-Willi syndrome subjects with differing genetic subtypes.

Henkhaus RS et al.

Journal of Neurodevelopmental Disorders, 2010

Risk-taking behavior in a gambling task associated with variations in the tryptophan hydroxylase 2 gene: relevance to psychiatric disorders.

Juhasz G et al.

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2010

Tph2 gene variants modulate response control processes in adult ADHD patients and healthy individuals.

Baehne CG et al.

Molecular Psychiatry, 2009

TPH2 -703G/T SNP may have important effect on susceptibility to suicidal behavior in major depression.

Yoon HK et al.

Progress in Neuro-psychopharmacology & Biological Psychiatry, 2009

Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment.

Tzvetkov MV et al.

Pharmacogenetics and Genomics, 2008

Functional characterization of the human TPH2 5' regulatory region: untranslated region and polymorphisms modulate gene expression in vitro.

Chen GL et al.

Human Genetics, 2008

The interaction between TPH2 promoter haplotypes and clinical-demographic risk factors in suicide victims with major psychoses.

De Luca V et al.

Genes, Brain, and Behavior, 2006

Promoter polymorphism of second tryptophan hydroxylase isoform (TPH2) in schizophrenia and suicidality.

De Luca V et al.

Psychiatry Research, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."