Associated Papers
The Genetic Mosaic of Depression: Linking Polymorphisms to Neuroplasticity and Stress Regulation.
Bednářová A et al.
Pharmaceuticals (basel, Switzerland), 2026
TPH2-703 G/T polymorphism is associated with stress, depression, and psychosocial symptoms in mentally healthy Mexicans.
Hernandez-Mixteco M et al.
Brain Research, 2023
Genetics of Functional Seizures; A Scoping Systematic Review.
Asadi-Pooya AA et al.
Genes, 2023
Prevalence of Common Alleles of Some Stress Resilience Genes among Adolescents Born in Different Periods Relative to the Socioeconomic Crisis of the 1990s in Russia.
Mikhailova SV et al.
Current Issues in Molecular Biology, 2022
Functional neurological disorder: new subtypes and shared mechanisms.
Hallett M et al.
The Lancet. Neurology, 2022
Predation Stress Causes Excessive Aggression in Female Mice with Partial Genetic Inactivation of Tryptophan Hydroxylase-2: Evidence for Altered Myelination-Related Processes.
Svirin E et al.
Cells, 2022
Association of Serotonergic Pathway Gene Polymorphisms With Behavioral Parameters in Patients With Opioid Dependence.
Sarkar S et al.
Cureus, 2021
Serotonin and early life stress interact to shape brain architecture and anxious avoidant behavior - a TPH2 imaging genetics approach.
Liu C et al.
Psychological Medicine, 2021
Association of orexin/hypocretin receptor gene (HCRTR1) with reward sensitivity, and interaction with gender.
Pulver A et al.
Brain Research, 2020
Effects of TPH2 gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders.
Spagnolo PA et al.
Journal of Neurology, Neurosurgery, and Psychiatry, 2020
Variants of the Aggression-Related RBFOX1 Gene in a Population Representative Birth Cohort Study: Aggressiveness, Personality, and Alcohol Use Disorder.
Vaht M et al.
Frontiers in Psychiatry, 2020
Tryptophan hydroxylase 2 as a therapeutic target for psychiatric disorders: focus on animal models.
Kulikova EA et al.
Expert Opinion on Therapeutic Targets, 2019
Serotonergic neurotransmission manipulation for the understanding of brain development and function: Learning from Tph2 genetic models.
Pratelli M et al.
Biochimie, 2019
Association of polymorphisms in HTR2A, TPH1, and TPH2 genes with attempted suicide in rural China.
Pan YF et al.
Psychiatric Genetics, 2019
Single nucleotide polymorphisms, variable number tandem repeats and allele influence on serotonergic enzyme modulators for aggressive and suicidal behaviors: A review.
Xiang C et al.
Pharmacology, Biochemistry, and Behavior, 2019
Association of Regulatory and Adaptive Status in Humans with Serotonergic Transmitter System Gene Polymorphism.
Pokrovskii VM et al.
Bulletin of Experimental Biology and Medicine, 2019
The Interaction of TPH2 and 5-HT2A Polymorphisms on Major Depressive Disorder Susceptibility in a Chinese Han Population: A Case-Control Study.
Yang J et al.
Frontiers in Psychiatry, 2019
No effect of C1473G polymorphism in the tryptophan hydroxylase 2 gene on the response of the brain serotonin system to chronic fluoxetine treatment in mice.
Bazhenova EY et al.
Neuroscience Letters, 2017
Association of regulatory TPH2 polymorphisms with higher reduction in depressive symptoms in children and adolescents treated with fluoxetine.
Gassó P et al.
Progress in Neuro-psychopharmacology & Biological Psychiatry, 2017
Nice guys: Homozygocity for the TPH2 -703G/T (rs4570625) minor allele promotes low aggressiveness and low anxiety.
Laas K et al.
Journal of Affective Disorders, 2017
Serotonin and the Brain's Rich Club-Association Between Molecular Genetic Variation on the TPH2 Gene and the Structural Connectome.
Markett S et al.
Cerebral Cortex (new York, N.y. : 1991), 2017
Association of Polymorphisms of Serotonin Transporter (5HTTLPR) and 5-HT2C Receptor Genes with Criminal Behavior in Russian Criminal Offenders.
Toshchakova VA et al.
Neuropsychobiology, 2017
Interaction of tryptophan hydroxylase 2 gene and life events in susceptibility to major depression in a Chinese Han population.
Ma J et al.
Journal of Affective Disorders, 2015
Association study of TPH2 polymorphisms and bipolar disorder in the Han Chinese population.
Chen S et al.
Progress in Neuro-psychopharmacology & Biological Psychiatry, 2015
B vitamin polymorphisms and behavior: evidence of associations with neurodevelopment, depression, schizophrenia, bipolar disorder and cognitive decline.
Mitchell ES et al.
Neuroscience and Biobehavioral Reviews, 2014
Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis.
González-Castro TB et al.
Bmc Psychiatry, 2014
Regulatory variant of the TPH2 gene and early life stress are associated with heightened attention to social signals of fear in infants.
Forssman L et al.
Journal of Child Psychology and Psychiatry, and Allied Disciplines, 2014
Variation in key genes of serotonin and norepinephrine function predicts gamma-band activity during goal-directed attention.
Enge S et al.
Cerebral Cortex (new York, N.y. : 1991), 2014
TPH2 gene polymorphisms in the regulatory region are associated with paranoid schizophrenia in Northern Han Chinese.
Xu XM et al.
Genetics and Molecular Research : Gmr, 2014
Gender-specific association between the COMT Val158Met polymorphism and openness to experience in panic disorder patients.
Konishi Y et al.
Neuropsychobiology, 2014
Association of 5HTR1A gene variants with suicidal behavior: case-control study and updated meta-analysis.
González-Castro TB et al.
Journal of Psychiatric Research, 2013
Associations between prefrontal γ-aminobutyric acid concentration and the tryptophan hydroxylase isoform 2 gene, a panic disorder risk allele in women.
Preuss N et al.
The International Journal of Neuropsychopharmacology, 2013
Epistatic interaction between 5HTTLPR and TPH2 polymorphisms predicts novelty seeking in women with bulimia nervosa spectrum disorders.
Thaler L et al.
Psychiatry Research, 2013
Genetic and neurocognitive foundations of emotion abnormalities in bipolar disorder.
Van Rheenen TE et al.
Cognitive Neuropsychiatry, 2013
Involvement of tryptophan hydroxylase 2 gene polymorphisms in susceptibility to tic disorder in Chinese Han population.
Zheng P et al.
Behavioral and Brain Functions : Bbf, 2013
Genetic variation at the TPH2 gene influences impulsivity in addition to eating disorders.
Slof-Op't Landt MC et al.
Behavior Genetics, 2013
Synergistic effects of COMT and TPH2 on social cognition.
Lin CH et al.
Psychiatry, 2013
Association between the COMT gene and rumination in a Hungarian sample.
Pap D et al.
Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet Lapja = Official Journal of the Hungarian Association of Psychopharmacology, 2012
Fluoxetine pharmacogenetics in child and adult populations.
Blazquez A et al.
European Child & Adolescent Psychiatry, 2012
The association of attempted suicide with genetic variants in the SLC6A4 and TPH genes depends on the definition of suicidal behavior: a systematic review and meta-analysis.
Clayden RC et al.
Translational Psychiatry, 2012
A common TPH2 haplotype regulates the neural processing of a cognitive control demand.
Kennedy AP et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2012
Melatonin pathway genes are associated with progressive subtypes and disability status in multiple sclerosis among Finnish patients.
Natarajan R et al.
Journal of Neuroimmunology, 2012
A functional Tph2 C1473G polymorphism causes an anxiety phenotype via compensatory changes in the serotonergic system.
Berger SM et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2012
Hopelessness, a potential endophenotpye for suicidal behavior, is influenced by TPH2 gene variants.
Lazary J et al.
Progress in Neuro-psychopharmacology & Biological Psychiatry, 2012
The c.1460C>T polymorphism of MAO-A is associated with the risk of depression in postmenopausal women.
Słopień R et al.
Thescientificworldjournal, 2012
Catechol-O-methyltransferase val158met polymorphism predicts placebo effect in irritable bowel syndrome.
Hall KT et al.
Plos One, 2012
Serotonin and early cognitive development: variation in the tryptophan hydroxylase 2 gene is associated with visual attention in 7-month-old infants.
Leppänen JM et al.
Journal of Child Psychology and Psychiatry, and Allied Disciplines, 2011
Effect of serotonin-related gene polymorphisms on pathogenesis and treatment response in Korean schizophrenic patients.
Kim YK et al.
Behavior Genetics, 2011
TPH2 G/T polymorphism is associated with hyperphagia, IQ, and internalizing problems in Prader-Willi syndrome.
Dykens EM et al.
Journal of Child Psychology and Psychiatry, and Allied Disciplines, 2011
Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome.
Jun S et al.
Neurogastroenterology and Motility, 2011