Associated Papers
Relationship Between Thiopurine S-Methyltransferase Genotype and Phenotype in Pediatric Acute Lymphoblastic Leukemia in Addis Ababa, Ethiopia.
Ali AM et al.
The Journal of Pediatric Pharmacology and Therapeutics : Jppt : the Official Journal of Ppag, 2025
Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.
Yang W et al.
Jama Network Open, 2022
A bioinformatics approach to the identification of novel deleterious mutations of human TPMT through validated screening and molecular dynamics.
Saxena S et al.
Scientific Reports, 2022
Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.
Lanillos J et al.
Npj Genomic Medicine, 2022
Importance of NUDT15 Polymorphisms in Thiopurine Treatments.
Tanaka Y et al.
Journal of Personalized Medicine, 2021
Pharmacogenetic studies of thiopurine methyltransferase genotype-phenotype concordance and effect of methotrexate on thiopurine metabolism.
Zimdahl Kahlin A et al.
Basic & Clinical Pharmacology & Toxicology, 2021
Thiopurine Drugs in the Treatment of Ulcerative Colitis: Identification of a Novel Deleterious Mutation in TPMT.
Harmand PO et al.
Genes, 2020
Comparison of Direct Sequencing, Real-Time PCR-High Resolution Melt (PCR-HRM) and PCR-Restriction Fragment Length Polymorphism (PCR-RFLP) Analysis for Genotyping of Common Thiopurine Intolerant Variant Alleles NUDT15 c.415C>T and TPMT c.719A>G (TPMT*3C).
Fong WY et al.
Diagnostics (basel, Switzerland), 2017
One amino acid makes a difference-Characterization of a new TPMT allele and the influence of SAM on TPMT stability.
Iu YPH et al.
Scientific Reports, 2017
Multidrug resistance protein 4 (MRP4) polymorphisms impact the 6-mercaptopurine dose tolerance during maintenance therapy in Japanese childhood acute lymphoblastic leukemia.
Tanaka Y et al.
The Pharmacogenomics Journal, 2015
Methylenetetrahydrofolate reductase gene haplotypes affect toxicity during maintenance therapy for childhood acute lymphoblastic leukemia in Japanese patients.
Tanaka Y et al.
Leukemia & Lymphoma, 2014
Thiopurine S-methyltransferase gene (TMPT) polymorphisms in a Mexican population of healthy individuals and leukemic patients.
Taja-Chayeb L et al.
Medical Oncology (northwood, London, England), 2008
Do the distribution patterns of polymorphisms at the thiopurine S-methyltransferase locus in sub-Saharan populations need revision? Hints from Cabinda and Mozambique.
Oliveira E et al.
European Journal of Clinical Pharmacology, 2007
Pharmacogenetics for individualized cancer chemotherapy.
Efferth T et al.
Pharmacology & Therapeutics, 2005
Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy.
Evans WE
Therapeutic Drug Monitoring, 2004
Frequency of thiopurine S-methyltransferase genetic variation in Thai children with acute leukemia.
Hongeng S et al.
Medical and Pediatric Oncology, 2000