Associated Papers
Population-Specific Distribution of TPMT Deficiency Variants and Ancestry Proportions in Ecuadorian Ethnic Groups: Towards Personalized Medicine.
Gallardo-Cóndor J et al.
Therapeutics and Clinical Risk Management, 2023
Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.
Kim B et al.
Translational and Clinical Pharmacology, 2021
Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.
Aboul-Soud MAM et al.
Saudi Journal of Biological Sciences, 2021
Targeted next generation sequencing as a tool for precision medicine.
Gulilat M et al.
Bmc Medical Genomics, 2019
Thiopurine-induced toxicity is associated with dysfunction variant of the human molybdenum cofactor sulfurase gene (xanthinuria type II).
Stiburkova B et al.
Toxicology and Applied Pharmacology, 2018
Assessing the capability of massively parallel sequencing for opportunistic pharmacogenetic screening.
Ng D et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2017
Genes implicated in thiopurine-induced toxicity: Comparing TPMT enzyme activity with clinical phenotype and exome data in a paediatric IBD cohort.
Coelho T et al.
Scientific Reports, 2016
A Simple Method for TPMT and ITPA Genotyping Using Multiplex HRMA for Patients Treated with Thiopurine Drugs.
Skrzypczak-Zielinska M et al.
Molecular Diagnosis & Therapy, 2016
Clinically relevant genetic variants of drug-metabolizing enzyme and transporter genes detected in Thai children and adolescents with autism spectrum disorder.
Medhasi S et al.
Neuropsychiatric Disease and Treatment, 2016
High-resolution melting analysis of the TPMT gene: a study in the Polish population.
Skrzypczak-Zielinska M et al.
Genetic Testing and Molecular Biomarkers, 2013
A new thiopurine s-methyltransferase haplotype associated with intolerance to azathioprine.
Colleoni L et al.
Journal of Clinical Pharmacology, 2013
[Thiopurine S-methyltransferase gene sequence analysis of ALL children severely intolerant to 6-mercaptopurine].
Ma XL et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2012
Characterization of a novel TPMT mutation associated with azathioprine-induced myelosuppression.
de Beaumais TA et al.
British Journal of Clinical Pharmacology, 2009
Molecular analysis of thiopurine S-methyltransferase alleles in South-east Asian populations.
Chang JG et al.
Pharmacogenetics, 2002