Associated Papers
Comparative assessment of anti-cancer drugs against NUDT15 variants to prevent leucopenia side effect in leukemia patients.
V J et al.
Journal, Genetic Engineering & Biotechnology, 2023
ABCC4, ITPA, NUDT15, TPMT and their interaction as genetic predictors of 6-mercaptopurine intolerance in chinese patients with acute lymphoblastic leukemia.
Fan POL et al.
Pediatric Hematology and Oncology, 2022
Pharmacogenetics of Drugs Used in the Treatment of Cancers.
Franczyk B et al.
Genes, 2022
NUDT15 polymorphism in healthy children with Bai nationality in Yunnan of China.
Pu G et al.
Pediatrics International : Official Journal of the Japan Pediatric Society, 2021
Genome wide association studies for treatment-related adverse effects of pediatric acute lymphoblastic leukemia.
Franca R et al.
Wires Mechanisms of Disease, 2021
NUDT15 gene variants and thiopurine-induced leukopenia in patients with inflammatory bowel disease.
Matsuoka K
Intestinal Research, 2020
High-resolution melt analysis enables simple genotyping of complicated polymorphisms of codon 18 rendering the NUDT15 diplotype.
Kakuta Y et al.
Journal of Gastroenterology, 2020
[Significance of NUDT15 gene in individualized treatment with 6-mercaptopurine in children with acute lymphoblastic leukemia].
He J et al.
Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics, 2019
Association between the c.415C > T, c.52G > A, and 36_37insGGAGTC polymorphisms of NUDT 15 and thiopurine-induced leukopenia, thiopurine intolerance, and severe hair loss: an updated meta-analysis.
Wang R et al.
Drug Design, Development and Therapy, 2019
NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.
Kakuta Y et al.
Journal of Gastroenterology, 2018
SMAD4 and NF1 mutations as potential biomarkers for poor prognosis to cetuximab-based therapy in Chinese metastatic colorectal cancer patients.
Mei Z et al.
Bmc Cancer, 2018
Pharmacogenetics of thiopurines for inflammatory bowel disease in East Asia: prospects for clinical application of NUDT15 genotyping.
Kakuta Y et al.
Journal of Gastroenterology, 2018
Influence of NUDT15 variants on hematological pictures of patients with inflammatory bowel disease treated with thiopurines.
Kojima Y et al.
World Journal of Gastroenterology, 2018
Predictive role of NUDT15 variants on thiopurine-induced myelotoxicity in Asian inflammatory bowel disease patients.
Sutiman N et al.
Pharmacogenomics, 2018
Emerging role of NUDT15 polymorphisms in 6-mercaptopurine metabolism and dose related toxicity in acute lymphoblastic leukaemia.
Singh M et al.
Leukemia Research, 2017
Pharmacogenetic Predictors of Treatment-Related Toxicity Among Children With Acute Lymphoblastic Leukemia.
Maxwell RR et al.
Current Hematologic Malignancy Reports, 2017
Nucleoside diphosphate-linked moiety X-type motif 15 C415T variant as a predictor for thiopurine-induced toxicity in Indian patients.
Shah SA et al.
Journal of Gastroenterology and Hepatology, 2017
Analysis of Thiopurine S-Methyltransferase Deficient Alleles in Acute Lymphoblastic Leukemia Patients in Mexican Patients.
Jiménez-Morales S et al.
Archives of Medical Research, 2016
Genetic polymorphisms of CYP2B6 affect the pharmacokinetics/pharmacodynamics of cyclophosphamide in Japanese cancer patients.
Nakajima M et al.
Pharmacogenetics and Genomics, 2007