Associated Papers
Pharmacogenetic Analysis of TPMT and NUDT15 in a European Pediatric Cohort with IBD and Autoimmune Diseases: Frequency Data and Clinical Relevance.
Pau A et al.
Genes, 2025
NUDT15 polymorphism in healthy children with Bai nationality in Yunnan of China.
Pu G et al.
Pediatrics International : Official Journal of the Japan Pediatric Society, 2021
Genome wide association studies for treatment-related adverse effects of pediatric acute lymphoblastic leukemia.
Franca R et al.
Wires Mechanisms of Disease, 2021
NUDT15 gene variants and thiopurine-induced leukopenia in patients with inflammatory bowel disease.
Matsuoka K
Intestinal Research, 2020
Association between the c.415C > T, c.52G > A, and 36_37insGGAGTC polymorphisms of NUDT 15 and thiopurine-induced leukopenia, thiopurine intolerance, and severe hair loss: an updated meta-analysis.
Wang R et al.
Drug Design, Development and Therapy, 2019
Influence of NUDT15 variants on hematological pictures of patients with inflammatory bowel disease treated with thiopurines.
Kojima Y et al.
World Journal of Gastroenterology, 2018
Nucleoside diphosphate-linked moiety X-type motif 15 C415T variant as a predictor for thiopurine-induced toxicity in Indian patients.
Shah SA et al.
Journal of Gastroenterology and Hepatology, 2017
NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.
Moriyama T et al.
Nature Genetics, 2016
Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity.
Rehling D et al.
The Journal of Biological Chemistry, 0
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