Associated Papers
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.
Dand N et al.
Nature Communications, 2025
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.
Dand N et al.
Medrxiv : the Preprint Server for Health Sciences, 2023
Genetic underpinnings of the psoriatic spectrum.
Hüffmeier U et al.
Medizinische Genetik : Mitteilungsblatt Des Berufsverbandes Medizinische Genetik E.v, 2023
A Familial Novel Putative-Pathogenic Mutation Identified in Plaque-Psoriasis by a Multigene Panel Analysis.
Nunziato M et al.
International Journal of Molecular Sciences, 2023
FinnGen provides genetic insights from a well-phenotyped isolated population.
Kurki MI et al.
Nature, 2023
Allosteric inhibition of SHP2 uncovers aberrant TLR7 trafficking in aggravating psoriasis.
Zhu Y et al.
Embo Molecular Medicine, 2022
Multidisciplinary In-Depth Investigation in a Young Athlete Suffering from Syncope Caused by Myocardial Bridge.
Brancaccio M et al.
Diagnostics (basel, Switzerland), 2021
Two patients with chronic mucocutaneous candidiasis caused by TRAF3IP2 deficiency.
Shafer S et al.
The Journal of Allergy and Clinical Immunology, 2021
Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease.
Kim YW et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2021
Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis.
Heng AHS et al.
Bmc Medical Genomics, 2021
Psoriasis Caught in the NET.
Di Domizio J et al.
The Journal of Investigative Dermatology, 2019
Neutrophil Extracellular Traps Induce Human Th17 Cells: Effect of Psoriasis-Associated TRAF3IP2 Genotype.
Lambert S et al.
The Journal of Investigative Dermatology, 2019
The Genetics of Psoriasis and Psoriatic Arthritis.
O'Rielly DD et al.
The Journal of Rheumatology. Supplement, 2019
The Act1 D10N missense variant impairs CD40 signaling in human B-cells.
Yu N et al.
Genes and Immunity, 2019
Novel compound heterozygous MYO7A mutations in Moroccan families with autosomal recessive non-syndromic hearing loss.
Bakhchane A et al.
Plos One, 2017
Phenome-wide association study using research participants' self-reported data provides insight into the Th17 and IL-17 pathway.
Ehm MG et al.
Plos One, 2017
Association with Genetic Variants in the IL-23 and NF-κB Pathways Discriminates between Mild and Severe Psoriasis Skin Disease.
Nikamo P et al.
The Journal of Investigative Dermatology, 2015
Sequence and analysis of a whole genome from Kuwaiti population subgroup of Persian ancestry.
Thareja G et al.
Bmc Genomics, 2015
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
Tang X et al.
Nucleic Acids Research, 2014
The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling.
Wu L et al.
Journal of Immunology (baltimore, Md. : 1950), 2014
Genetic polymorphism in the TRAF3IP2 gene is associated with psoriasis vulgaris in a Japanese population.
Hayashi M et al.
Journal of Dermatological Science, 2014
An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.
Boisson B et al.
Immunity, 2013
The genetics of psoriasis and psoriatic arthritis.
Chandran V
Clinical Reviews in Allergy & Immunology, 2013
The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90.
Wang C et al.
Nature Immunology, 2013
New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis.
Doyle MS et al.
Arthritis Research & Therapy, 2012
Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization.
Böhm B et al.
Arthritis Research & Therapy, 2012
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.
Hüffmeier U et al.
Nature Genetics, 2010