Associated Papers
A Cohort Study of CNS Tumors in Multiple Endocrine Neoplasia Type 1.
Graillon T et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2024
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.
Youngblood MW et al.
Nature Communications, 2023
Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease.
Mishra-Gorur K et al.
Proceedings of the National Academy of Sciences of the United States of America, 2023
Mutated KLF4(K409Q) in meningioma binds STRs and activates FGF3 gene expression.
Tsytsykova AV et al.
Iscience, 2022
Prognostic impact of genetic alterations and methylation classes in meningioma.
Berghoff AS et al.
Brain Pathology (zurich, Switzerland), 2022
Targeted deep sequencing of DNA from multiple tissue types improves the diagnostic rate and reveals a highly diverse phenotype of mosaic neurofibromatosis type 2.
Teranishi Y et al.
Journal of Medical Genetics, 2021
Loss-of-Function Mutations in TRAF7 and KLF4 Cooperatively Activate RAS-Like GTPase Signaling and Promote Meningioma Development.
Najm P et al.
Cancer Research, 2021
Phenotypic spectrum and transcriptomic profile associated with germline variants in TRAF7.
Castilla-Vallmanya L et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2020
Well-Differentiated Papillary Mesothelioma of the Peritoneum Is Genetically Distinct from Malignant Mesothelioma.
Shrestha R et al.
Cancers, 2020
Phase and context shape the function of composite oncogenic mutations.
Gorelick AN et al.
Nature, 2020
Non-NF2 mutations have a key effect on inhibitory immune checkpoints and tumor pathogenesis in skull base meningiomas.
Hao S et al.
Journal of Neuro-oncology, 2019
Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42.
Stevers M et al.
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2019
Whole exome sequencing of multiple meningiomas with varying histopathological presentation in one patient revealed distinctive somatic mutation burden and independent clonal origins.
Sheng HS et al.
Cancer Management and Research, 2019
Diffuse midline skull base meningiomas: identification of a rare and aggressive subgroup of meningiomas.
Peyre M et al.
Journal of Neuro-oncology, 2017
Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO.
Clark VE et al.
Science (new York, N.y.), 2013
Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.
Reuss DE et al.
Acta Neuropathologica, 2013